Fibrinólisis primaria o secundaria

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Definición

La fibrinólisis es un proceso corporal normal que impide que los coágulos sanguíneos que ocurren en forma natural crezcan y causen problemas.

La fibrinólisis primaria se refiere a la descomposición normal de los coágulos.

La fibrinólisis secundaria es la descomposición de los coágulos sanguíneos debido a un trastorno de salud, un medicamento u otra causa. Esto puede provocar sangrado intenso.

Nombres alternativos

Fibrinólisis primaria; Fibrinólisis secundaria

Causas

Los coágulos de sangre se forman en una proteína llamada fibrina. La descomposición de la fibrina (fibrinólisis) puede deberse a:

  • Infecciones bacterianas
  • Cáncer
  • Ejercicio intenso
  • Bajo azúcar en la sangre
  • Oxigenación insuficiente a los tejidos

El médico puede darle medicamentos para ayudar a que los coágulos sanguíneos se descompongan más rápidamente. Esto se puede hacer si un coágulo de sangre provoca un ataque cardíaco.

Referencias

Schafer AI. Hemorrhagic disorders. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 175.

Weitz JI. Hemostasis, Thrombosis, fibrinolysis, and cardiovascular disease. In: Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 10th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 82.

Weitz JI. Overview of hemostasis and thrombosis. In: Hoffman R, Benz EJ Jr., Silberstein LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2013:chap 124.

Version Info

  • Last reviewed on 2/1/2016
  • Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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