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Asthma medications - theophylline derivatives

• Medications
• Depletions
• Editorial Note
• Supporting Research

Medications

• Aminophylline
  • Truphylline®
• Theophylline
  • Aerolate III®
  • Aerolate JR®
  • Aerolate SR®
  • Elixophyllin®
  • Quibron®-T
  • Quibron®-T/SR
  • Respbid®
  • Slo-bid™
  • Slo-Phyllin®
  • T-Phyl®
  • Theo-24®
  • Theo-Dur®
  • Theochron®
  • Theolair™
  • Uni-Dur®
  • Uniphyl®

Depletions

Vitamin B6 (Pyridoxine)

Symptoms of vitamin B ₆ deficiency may include weakness, nervousness, insomnia, mental confusion, irritability, and anemia. Long-term low levels of this nutrient may also increase the risk of heart disease as well as colon and prostate cancers.

Editorial Note

The selected depletions information presented here identifies some of the nutrients that may be depleted by certain medications. The signs and symptoms associated with nutrient deficiency may also indicate conditions other than nutrient deficiency. If you are experiencing any of the signs or symptoms mentioned, it does not necessarily mean that you are nutrient deficient. Nutrient depletion depends upon a number of factors, including your medical history, diet, and lifestyle as well as the length of time you have been taking the medication. Please consult your healthcare provider; he or she can best assess and address your individual healthcare needs, and determine if you are at risk for nutrient depletions from these medications as well as others not listed here.

Supporting Research

Ames BN. Micronutrient deficiencies: A major cause of DNA damage. Ann NY Acad Sci . 2000;889:87-106.

Covington T, ed. Nonprescription Drug Therapy Guiding Patient Self-Care . St Louis, MO: Facts and Comparisons; 1999:467-545.

Delport, R. et al. Vitamin B6 nutritional status in asthma: The effect of theophylline therapy on plasma pyridoxal-51 –phosphate and pyridoxal levels. Int. J. Vitam. Nutr. Res. 58(1):67-72, 1988.

National Research Council. Recommended Dietary Allowances . 10 ^th ed. Washington, DC: National Academy Press; 1989.

Wilson JD. Vitamin deficiency and excess. In: Fauci AS, Braunwald E, Isselbacher KJ, et al, eds. Harrison's Principles of Internal Medicine . 14 ^th ed. New York: McGraw-Hill Companies Health Professional Division; 1998:483-485.

• Review Date: 10/1/2000
• Reviewed By: All depletions monographs have been reviewed by a team of experts including Derrick M. DeSilva, Jr., MD, Raritan Bay Medical Center, Perth Amboy, NJ; Jacqueline A. Hart, MD, Department of Internal Medicine, Newton-Wellesley Hospital, Harvard University and Senior Medical Editor, A.D.A.M., Inc., Boston, MA; John Hinze, PharmD, NMD, Woodbine, IA; Ruth Marlin, MD, Medical Director and Director of Medical Education, Preventive Medicine Research Institute, Sausalito, CA; Brian T Sanderoff, PD, BS in Pharmacy, Clinical Assistant Professor, University of Maryland School of Pharmacy; President, Your Prescription for Health, Owings Mills, MD; Leonard Wisneski, MD, FACP, George Washington University, Rockville, MD; Ira Zunin, MD, MPH, MBA, President and Chairman, Hawaii State Consortium for Integrative Medicine, Honolulu, HI.

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