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Note: The resources listed in this guide are not intended to be fully systematic or complete, nor does inclusion here imply any endorsement or recommendation by The University of Maryland or the Center for Integrative Medicine. The University of Maryland and the Center for Integrative Medicine make no warranties, express or implied, about the value or utility for any purpose of the information and resources contained herein.

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Possible Interactions with: Carnitine (L-Carnitine)

Interactions:

If you are currently being treated with any of the following medications, you should not use carnitine without first talking to your health care provider.

AZT -- In a laboratory study, L-carnitine supplements protected muscle tissue against toxic side effects from AZT, a medication used to treat HIV and AIDS. Additional studies are needed to confirm whether L-carnitine would also have this effect in people.

Doxorubicin -- Treatment with L-carnitine may protect heart cells against the toxic side effects of doxorubicin, a chemotherapy medication used to treat cancer, without reducing the effectiveness of medication. Always talk to your oncologist before combining any complementary or alternative therapy with chemotherapy.

Isotretinoin -- Isotretinoin (Accutane), a strong medication used for severe acne, can cause abnormalities in liver function, measured by a blood test, as well as high cholesterol and muscle pain and weakness. These symptoms are similar to those seen with carnitine deficiency. Researchers in Greece showed that a large group of people who had side effects from isotretinoin got better when taking L-carnitine compared to those who took a placebo.

Valproic acid -- The anticonvulsant medication valproic acid may lower blood levels of carnitine and can cause carnitine deficiency. Taking L-carnitine supplements may prevent any deficiency and may also reduce the side effects of valproic acid.

Drug Interactions:

DoxorubicinIsotretinoinValproic Acid and DerivativesZidovudine

Alternative Names:

Acetyl-L-Carnitine; Carnitine (L-Carnitine); L-Carnitine

  • Reviewed last on: 6/20/2007
  • Steven D. Ehrlich, N.M.D., private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
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