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Note: The resources listed in this guide are not intended to be fully systematic or complete, nor does inclusion here imply any endorsement or recommendation by The University of Maryland or the Center for Integrative Medicine. The University of Maryland and the Center for Integrative Medicine make no warranties, express or implied, about the value or utility for any purpose of the information and resources contained herein.

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Possible Interactions with: Willow Bark

Interactions/Depletions:

Because willow bark contains salicylates, it has the potential to interact with a number of drugs and herbs. Talk to your doctor before taking willow bark if you take any other medications, herbs, or supplements.

Willow bark may interact with any of the following:

Anticoagulants (blood-thinning medications) -- Willow bark may strengthen the effects of drugs and herbs with blood-thinning properties.

Beta blockers -- including Atenolol (Tenormin), Metoprolol (Lopressor, Toprol-XL), Propranolol (Inderal, Inderal LA). Willow bark may reduce the effectiveness of these drugs.

Diuretics (water pills) -- Willow bark may reduce the effectiveness of these drugs.

Nonsteroidal anti-inflammatory drugs -- including ibuprofen (Advil, Motrin) and naproxen (Aleve). Taking willow bark with these drugs may increase risk of stomach bleeding.

Methotrexate and phenytoin (Dilantin) -- Willow may increase levels of these drugs in the body, resulting in toxic levels.

Drug Interactions:

AspirinBlood-thinning Medications

Alternative Names:

Crack willow; European willow; Liu-zhi; Purple willow; Pussy willow; Salix alba; Salix nigra; Wheeping willow; White willow

  • Reviewed last on: 2/13/2007
  • Steven D. Ehrlich, N.M.D., private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
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