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Pronunciation:

(a LOO mi num hye DROKS ide & mag NEE zhum KAR bun nate)

U.S. Brand Names:

Gaviscon® Extra Strength [OTC]; Gaviscon® Liquid [OTC]

Synonyms:

Magnesium Carbonate and Aluminum Hydroxide

Generic Available:

Yes

Use:

Temporary relief of symptoms associated with gastric acidity

Adverse Reactions:

1% to 10%:

Endocrine & metabolic: Hypermagnesemia, aluminum intoxication (prolonged use and concomitant renal failure), hypophosphatemia

Gastrointestinal: Constipation, diarrhea

Neuromuscular & skeletal: Osteomalacia

Drug Interactions:

Decreased effect: Tetracyclines, digoxin, indomethacin, or iron salts, isoniazid, allopurinol, benzodiazepines, corticosteroids, penicillamine, phenothiazines, ranitidine, ketoconazole, itraconazole

Dosage:

Oral: Adults:

Liquid:

Gaviscon® Regular Strength: 15-30 mL 4 times/day after meals and at bedtime

Gaviscon® Extra Strength Relief: 15-30 mL 4 times/day after meals

Tablet (Gaviscon® Extra Strength Relief): Chew 2-4 tablets 4 times/day

Dietary Considerations:

Should be taken 1-3 hours after meals with water, milk or juice. Products contain sodium (0.57 mEq/5 mL regular strength liquid, 0.9 mEq/5 mL extra strength liquid, 1.3 mEq extra strength tablet).

Patient Education:

Liquid: Shake well. Do not use if you are on a sodium-restricted diet.

Tablet: Take tablets after meals and at bedtime, or as needed. Chew tablet, do not swallow whole. Follow tablets with ¹/2 glass of water.

Nursing Implications:

Monitor stool frequency

Dental Health: Effects on Dental Treatment:

Key adverse event(s) related to dental treatment: Chalky taste. Aluminum and magnesium ions prevent GI absorption of tetracycline by forming a large ionized chelated molecule with the tetracyclines in the stomach. Aluminum hydroxide prevents GI absorption of ketoconazole and itraconazole by increasing the pH in the GI tract. Any of these drugs should be administered at least 1 hour before aluminum hydroxide.

Dental Health: Vasoconstrictor/Local Anesthetic Precautions:

No information available to require special precautions

Mental Health: Effects on Mental Status:

None reported

Mental Health: Effects on Psychiatric Treatment:

None reported

Dosage Forms:

Liquid:

Gaviscon®: Aluminum hydroxide 31.7 mg and magnesium carbonate 119.3 mg per 5 mL (355 mL) [contains sodium 0.57 mEq/5 mL]

Gaviscon® Extra Strength: Aluminum hydroxide 84.6 mg and magnesium carbonate 79.1 mg per 5 mL (355 mL) [contains sodium 0.9 mEq/5 mL]

Tablet, chewable (Gaviscon® Extra Strength): Aluminum hydroxide 160 mg and magnesium carbonate 105 mg [contains sodium 1.3 mEq/tablet]

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