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Pronunciation:

(a LOO mi num hye DROKS ide & mag NEE zhum trye SIL i kate)

U.S. Brand Names:

Alenic Alka Tablet [OTC]; Gaviscon® Tablet [OTC]; Genaton Tablet [OTC]

Synonyms:

Magnesium Trisilicate and Aluminum Hydroxide

Generic Available:

Yes

Use:

Temporary relief of hyperacidity

Pregnancy Risk Factor:

Drug Interactions:

Decreased effect: Tetracyclines, digoxin, indomethacin, or iron salts, isoniazid, allopurinol, benzodiazepines, corticosteroids, penicillamine, phenothiazines, ranitidine, ketoconazole, itraconazole

Dosage:

Oral: Adults: Chew 2-4 tablets 4 times/day or as directed by healthcare provider

Administration:

Tablets should be chewed and not swallowed whole.

Dietary Considerations:

Should be taken 1-3 hours after meals with water, milk, or juice. Gaviscon® chewable tablet contains sodium 0.8 mEq/tablet.

Patient Education:

Chew tablets; do not swallow whole

Dental Health: Effects on Dental Treatment:

Key adverse event(s) related to dental treatment: Chalky taste. Aluminum and magnesium ions prevent GI absorption of tetracycline by forming a large ionized chelated molecule with the tetracyclines in the stomach. Aluminum hydroxide prevents GI absorption of ketoconazole and itraconazole by increasing the pH in the GI tract. Any of these drugs should be administered at least 1 hour before aluminum hydroxide.

Dental Health: Vasoconstrictor/Local Anesthetic Precautions:

No information available to require special precautions

Mental Health: Effects on Mental Status:

None reported

Mental Health: Effects on Psychiatric Treatment:

None reported

Dosage Forms:

Tablet, chewable: Aluminum hydroxide 80 mg and magnesium trisilicate 20 mg

Alenic Alka: Aluminum hydroxide 80 mg and magnesium trisilicate 20 mg [butterscotch flavor]

Gaviscon®: Aluminum hydroxide 80 mg and magnesium trisilicate 20 mg [contains sodium 0.8 mEq/tablet; butterscotch flavor]

Genaton: Aluminum hydroxide 80 mg and magnesium trisilicate 20 mg

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