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Aluminum Hydroxide and Magnesium Trisilicate


Pronunciation

 (a LOO mi num hye DROKS ide & mag NEE zhum trye SIL i kate)


U.S. Brand Names

 Alenic Alka Tablet [OTC]; Gaviscon® Tablet [OTC]; Genaton Tablet [OTC]


Synonyms

 Magnesium Trisilicate and Aluminum Hydroxide


Generic Available

 Yes


Use

 Temporary relief of hyperacidity


Pregnancy Risk Factor

 C


Drug Interactions

 Decreased effect: Tetracyclines, digoxin, indomethacin, or iron salts, isoniazid, allopurinol, benzodiazepines, corticosteroids, penicillamine, phenothiazines, ranitidine, ketoconazole, itraconazole


Dosage

 Oral: Adults: Chew 2-4 tablets 4 times/day or as directed by healthcare provider


Administration

 Tablets should be chewed and not swallowed whole.


Dietary Considerations

 Should be taken 1-3 hours after meals with water, milk, or juice. Gaviscon® chewable tablet contains sodium 0.8 mEq/tablet.


Patient Education

 Chew tablets; do not swallow whole


Dental Health: Effects on Dental Treatment

 Key adverse event(s) related to dental treatment: Chalky taste. Aluminum and magnesium ions prevent GI absorption of tetracycline by forming a large ionized chelated molecule with the tetracyclines in the stomach. Aluminum hydroxide prevents GI absorption of ketoconazole and itraconazole by increasing the pH in the GI tract. Any of these drugs should be administered at least 1 hour before aluminum hydroxide.


Dental Health: Vasoconstrictor/Local Anesthetic Precautions

 No information available to require special precautions


Mental Health: Effects on Mental Status

 None reported


Mental Health: Effects on Psychiatric Treatment

 None reported


Dosage Forms

Tablet, chewable: Aluminum hydroxide 80 mg and magnesium trisilicate 20 mg

Alenic Alka: Aluminum hydroxide 80 mg and magnesium trisilicate 20 mg [butterscotch flavor]

Gaviscon®: Aluminum hydroxide 80 mg and magnesium trisilicate 20 mg [contains sodium 0.8 mEq/tablet; butterscotch flavor]

Genaton: Aluminum hydroxide 80 mg and magnesium trisilicate 20 mg


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