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Benazepril and Hydrochlorothiazide


Pronunciation

 (ben AY ze pril & hye droe klor oh THYE a zide)


U.S. Brand Names

 Lotensin® HCT


Synonyms

 Hydrochlorothiazide and Benazepril


Generic Available

 Yes


Use

 Treatment of hypertension


Pregnancy Risk Factor

 C/D (2nd and 3rd trimesters)


Pregnancy Implications

 See individual agents.


Lactation

 Enters breast milk/compatible


Adverse Reactions

 See individual agents.


Drug Interactions

 See individual agents.


Pharmacodynamics/Kinetics

 See individual agents.


Dosage

 Dose is individualized


Patient Education

 See individual agents. Pregnancy precaution: Do not get pregnant while taking this medication; use appropriate contraceptive measures.


Dental Health: Effects on Dental Treatment

 No significant effects or complications reported


Dental Health: Vasoconstrictor/Local Anesthetic Precautions

 No information available to require special precautions


Mental Health: Effects on Mental Status

 May cause drowsiness


Mental Health: Effects on Psychiatric Treatment

 May decrease lithium clearance resulting in an increase in serum lithium levels and potential lithium toxicity; monitor serum lithium levels


Dosage Forms

 Tablet:

5/6.25: Benazepril 5 mg and hydrochlorothiazide 6.25 mg

10/12.5: Benazepril 10 mg and hydrochlorothiazide 12.5 mg

20/12.5: Benazepril 20 mg and hydrochlorothiazide 12.5 mg

20/25: Benazepril 20 mg and hydrochlorothiazide 25 mg


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