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Pronunciation:

(sip roe FLOKS a sin & hye droe KOR ti sone)

U.S. Brand Names:

Cipro® HC

Synonyms:

Hydrocortisone and Ciprofloxacin

Generic Available:

Canadian Brand Names:

Cipro® HC

Use:

Treatment of acute otitis externa, sometimes known as "swimmer's ear"

Drug Interactions:

Ciprofloxacin: Inhibits CYP1A2 (strong), 3A4 (weak)

Hydrocortisone: Substrate of CYP3A4 (minor); Induces CYP3A4 (weak)

Also see individual agents.

Pharmacodynamics/Kinetics:

See individual agents.

Dosage:

Children >1 year of age and Adults: Otic: The recommended dosage for all patients is three drops of the suspension in the affected ear twice daily for seven day; twice-daily dosing schedule is more convenient for patients than that of existing treatments with hydrocortisone, which are typically administered three or four times a day; a twice-daily dosage schedule may be especially helpful for parents and caregivers of young children

Patient Education:

Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to become pregnant. Consult prescriber if breast-feeding.

Dental Health: Effects on Dental Treatment:

No significant effects or complications reported

Dental Health: Vasoconstrictor/Local Anesthetic Precautions:

No information available to require special precautions

Mental Health: Effects on Mental Status:

None reported

Mental Health: Effects on Psychiatric Treatment:

None reported

Dosage Forms:

Suspension, otic: Ciprofloxacin hydrochloride 0.2% and hydrocortisone 1% (10 mL) [contains benzyl alcohol]

International Brand Names:

Cipro® HC (CA)

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