U.S. Brand Names:

Doan's® [OTC]; Doan's® Extra Strength [OTC]; Keygesic [OTC]; Momentum® [OTC]

Generic Available:

Yes

Use:

Mild to moderate pain, fever, various inflammatory conditions

Warnings/Precautions:

Use with caution with bleeding disorders, renal dysfunction, dehydration, gastritis, or peptic ulcer disease. Heavy ethanol use (>3 drinks/day) can increase bleeding risks. Avoid use in renal or hepatic failure. Discontinue use if tinnitus or impaired hearing occurs. Patients with sensitivity to tartrazine dyes, nasal polyps, and asthma may have an increased risk of salicylate sensitivity. Surgical patients should avoid ASA if possible, for 1-2 weeks prior to surgery, to reduce the risk of excessive bleeding. Children and teenagers who have or are recovering from chickenpox or flu-like symptoms should not use this product. Changes in behavior (along with nausea and vomiting) may be an early sign of Reye's syndrome; patients should be instructed to contact their healthcare provider if these occur.

Dosage:

Oral: Children 12 years and Adults:

Doan's®: Two caplets every 4 hours as needed (maximum: 12 caplets/24 hours)

Doan's® Extra Strength, Momentum®: Two caplets every 6 hours (maximum: 8 caplets/24 hours)

Keygesic: One caplet every 4 hours as needed (maximum 4 caplets/24 hours)

Administration:

Administer with a full glass of water.

Reference Range:

Serum magnesium: 1.5-2.5 mg/dL; slightly different ranges are reported by different laboratories

Dental Health: Effects on Dental Treatment:

NSAID formulations are known to reversibly decrease platelet aggregation via mechanisms different than observed with aspirin. The dentist should be aware of the potential of abnormal coagulation. Caution should also be exercised in the use of NSAIDs in patients already on anticoagulant therapy with drugs such as warfarin (Coumadin®).

Dental Health: Vasoconstrictor/Local Anesthetic Precautions:

No information available to require special precautions

Mental Health: Effects on Mental Status:

None reported

Mental Health: Effects on Psychiatric Treatment:

None reported

International Brand Names:

Artrifen® (CO); Bexidermil® (ES); Dencorub® (AU); Enter-Sal® (TR); Metsal AR® (AU); Myoflex® (MX); Natrium Salicylicum Biotika® (CZ); Rati Salil E® (AR)