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Pronunciation:

(naf AZ oh leen & an TAZ oh leen)

U.S. Brand Names:

Vasocon-A® [OTC]

Synonyms:

Antazoline and Naphazoline

Generic Available:

Canadian Brand Names:

Albalon®-A Liquifilm; Vasocon-A®

Use:

Topical ocular congestion, irritation and itching

Pregnancy Risk Factor:

Contraindications:

Hypersensitivity to naphazoline, antazoline, or any component of the formulation; angle-closure glaucoma

Adverse Reactions:

Frequency not defined.

Cardiovascular: Systemic cardiovascular stimulation, hypertension

Central nervous system: Nervousness, dizziness, headache

Gastrointestinal: Nausea

Local: Transient stinging

Neuromuscular & skeletal: Weakness

Ocular: Mydriasis, increased intraocular pressure, blurred vision

Respiratory: Nasal mucosa irritation, dryness, rebound congestion

Miscellaneous: Diaphoresis

Drug Interactions:

MAO inhibitors (exaggerated adrenergic effects may result)

Stability:

Store in tight, light-resistant containers

Dosage:

Ophthalmic: 1-2 drops every 3-4 hours

Patient Education:

Do not use discolored solutions

Nursing Implications:

Do not use discolored solutions

Dental Health: Effects on Dental Treatment:

No significant effects or complications reported

Dental Health: Vasoconstrictor/Local Anesthetic Precautions:

No information available to require special precautions

Mental Health: Effects on Mental Status:

May cause nervousness or dizziness

Mental Health: Effects on Psychiatric Treatment:

TCAs and MAO inhibitors may potentiate the pressor response of decongestants; monitor for changes in response

Dosage Forms:

Solution, ophthalmic: Naphazoline hydrochloride 0.05% and antazoline phosphate 0.5% (15 mL) [contains benzalkonium chloride]

International Brand Names:

Albalon®-A Liquifilm (CA); Vasocon-A® (CA)

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