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Home > Medical Reference > Encyclopedia (English)



 

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Pronunciation:

(sye METH i kone)

U.S. Brand Names:

Alka-Seltzer® Gas Relief [OTC]; Baby Gasz [OTC]; Flatulex® [OTC]; Gas-X® [OTC]; Gas-X® Extra Strength [OTC]; Genasyme® [OTC]; Mylanta® Gas [OTC]; Mylanta® Gas Maximum Strength [OTC]; Mylicon® Infants [OTC]; Phazyme® Quick Dissolve [OTC]; Phazyme® Ultra Strength [OTC]

Synonyms:

Activated Dimethicone; Activated Methylpolysiloxane

Generic Available:

Yes: Tablet, suspension

Canadian Brand Names:

Ovol®; Phazyme™

Use:

Relieves flatulence and functional gastric bloating, and postoperative gas pains

Pregnancy Risk Factor:

C

Contraindications:

Hypersensitivity to simethicone or any component of the formulation

Adverse Reactions:

No data reported

Drug Interactions:

No data reported

Ethanol/Nutrition/Herb Interactions:

Food: Avoid carbonated beverages and gas-forming foods.

Stability:

Protect from light

Mechanism of Action:

Decreases the surface tension of gas bubbles thereby disperses and prevents gas pockets in the GI system

Dosage:

Oral:

Infants: 20 mg 4 times/day

Children <12 years: 40 mg 4 times/day

Children >12 years and Adults: 40-120 mg after meals and at bedtime as needed, not to exceed 500 mg/day

Administration:

Shake oral suspension (drops) before using; mix with water, infant formula, or other liquids.

Dietary Considerations:

Should be taken after meals.

Patient Education:

Some tablets may be chewed thoroughly before swallowing, follow with a glass of water

Dental Health: Effects on Dental Treatment:

No significant effects or complications reported

Dental Health: Vasoconstrictor/Local Anesthetic Precautions:

No information available to require special precautions

Mental Health: Effects on Mental Status:

None reported

Mental Health: Effects on Psychiatric Treatment:

None reported

Dosage Forms:

Softgels:

Alka-Seltzer® Gas Relief, Gas-X® Extra Strength, Mylanta® Gas Maximum Strength: 125 mg

Phazyme® Ultra Strength: 180 mg

Suspension, oral drops: 40 mg/0.6 mL (30 mL)

Baby Gasz, Genasyme®: 40 mg/0.6 mL (30 mL)

Flatulex®: 40 mg/0.6 mL (30 mL) [fruit flavor]

Mylicon® Infants: 40 mg/0.6 mL (30 mL) [alcohol free; contains sodium benzoate; available in a non-staining formula]

Tablet, chewable: 80 mg, 125 mg

Gas-X®: 80 mg [peppermint cr&egrave;me or sodium free cherry cr&egrave;me flavor]

Gas-X® Extra Strength: 125 mg [peppermint cr&egrave;me or cherry cr&egrave;me flavor]

Genasyme®: 80 mg

Mylanta® Gas: 80 mg [mint flavor]

Mylanta® Gas Extra Strength: 125 mg [cherry and mint flavors]

Phazyme® Quick Dissolve: 125 mg [contains 0.4 mg phenylalanine (as aspartame)/tablet; mint flavor]

International Brand Names:

Ovol® (CA); Phazyme™ (CA)

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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