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Pronunciation:

(tole NAF tate)

U.S. Brand Names:

Absorbine Jr.® Antifungal [OTC]; Aftate® Antifungal [OTC]; Blis-To-Sol® [OTC]; Dermasept Antifungal [OTC]; Fungi-Guard [OTC]; Gold Bond® Antifungal [OTC]; Tinactin® Antifungal [OTC]; Tinactin® Antifungal Jock Itch [OTC]; Tinaderm [OTC]; Ting® [OTC]; TipTapToe [OTC]

Generic Available:

Yes: Cream, powder, solution, swabs

Canadian Brand Names:

Pitrex

Use:

Treatment of tinea pedis, tinea cruris, tinea corporis

Pregnancy Risk Factor:

Contraindications:

Hypersensitivity to tolnaftate or any component of the formulation; nail and scalp infections

Warnings/Precautions:

For external use only; apply to clean, dry skin; keep away from eyes

Adverse Reactions:

Frequency not defined.

Dermatologic: Pruritus, contact dermatitis

Local: Irritation, stinging

Drug Interactions:

No data reported

Mechanism of Action:

Distorts the hyphae and stunts mycelial growth in susceptible fungi

Pharmacodynamics/Kinetics:

Onset of action: 24-72 hours

Dosage:

Children 2 years and Adults: Topical: Wash and dry affected area; spray aerosol or apply 1-3 drops of solution or a small amount of cream, gel, or powder and rub into the affected areas 2 times/day

Note: May use for up to 4 weeks for tinea pedis or tinea corporis, and up to 2 weeks for tinea cruris

Patient Education:

Avoid contact with the eyes; apply to clean dry area; consult the physician if a skin irritation develops or if the skin infection worsens or does not improve after 10 days of therapy; does not stain skin or clothing

Dental Health: Effects on Dental Treatment:

No significant effects or complications reported

Dental Health: Vasoconstrictor/Local Anesthetic Precautions:

No information available to require special precautions

Mental Health: Effects on Mental Status:

None reported

Mental Health: Effects on Psychiatric Treatment:

None reported

Dosage Forms:

Aerosol, liquid, topical:

Aftate®: 1% (120 mL) [contains alcohol]

Tinactin® Antifungal: 1% (120 mL) [contains alcohol]

Ting®: 1% (90 mL)

Aerosol, powder, topical:

Aftate®: 1% (105 g) [contains alcohol]

Tinactin® Antifungal: 1% (45 g, 90 g, 100 g, 150 g) [contains alcohol]

Tinactin® Antifungal Jock Itch: 1% (100 g) [contains alcohol]

Ting®: 1% (90 g)

Cream, topical: 1% (15 g, 30 g)

Fungi-Guard: 1% (15 g)

Tinactin® Antifungal: 1% (15 g, 30 g)

Tinactin® Antifungal Jock Itch: 1% (15 g)

Gel, topical (Absorbine Jr.® Antifungal): 1% (21 g)

Liquid, topical:

Blis-To-Sol®: 1% (30 mL, 55 mL)

Dermasept Antifungal: 1% (30 mL) [contains benzyl alcohol and benzoic acid]

Powder, topical: 1% (45 g)

Solution, topical: 1% (10 mL)

Absorbine Jr.® Antifungal: 1% (60 mL)

Tinaderm: 1% (10 mL)

Swab, topical [liquid-filled swabstick]: 1% (36s)

Gold Bond® Antifungal: 1% (24s)

TipTapToe: 1% (72s)

International Brand Names:

Aftate® (HK); Alber-T® (HK); Athlete's Foot® (AR, HU, IL); Bocima® (RO); Chinofungin® (HU); Curatin® (AU); Digifungin® (HU); Ezon-T® (TH); Focusan® (CZ); Hi-Alarzin® (HK, JP); Micoisdin® (ES); Miconaft® (RO); Mikoderm® (TR); Naftate® (ID); Pitrex (CA, IL); Ringworm Ointment® (AU); Scholl Athlete's Foot Cream® (GB); Scholl Athlete's Foot Powder® (GB); Scholl Athlete's Foot Spray® (GB); Separin® (JP); Sorgoa® (DE, LU); Sporiline® (FR); Tinactin® (CL); Tinaderm® (AU, BD, CL, EC, ES, IE, IN, IT, MX, NZ, SG, ZA); Tinasol® (IL); Tinatox® (DE); Tineafax® (AU); Tolnadem® (IN); Tolnaftato L.CH.® (CL); Tolnaftat Puder N® (DE); Tolsol® (IN); Tonoftal® (DE); Tono® (TH)

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