200094.dcr200094r.gifThis animation shows the passage of allergens (pollen) into the nasal cavity. The body response includes the release of histamine, a chemical that produces allergy symptoms in the body.Allergens like pollen are nothing more than foreign plant antigens. The stimulus for sneezing gets triggered when allergens first enter the nasal tissue. Pollen allergens encounter the plasma cells in the nose, which respond by producing antibodies. These antibodies attach to mast cells, which are white blood cells containing the chemical histamine. As more antibodies are produced, they cause the mast cells to release histamine.
Histamine then produces allergy symptoms. A stuffy and runny nose, sneezing and watery eyes help to remove the invading pollen. Medications called antihistamines may be used to help alleviate severe allergy symptoms.Allergies and AsthmaImmune SystemShockwave
200033.mov200033r.gifThis animation shows the brain and the changes that occur to it from Alzheimer's disease.
In a person with Alzheimer's Disease, neurofibrillary tangles and plaques develop causing both structural and chemical problems in the brain. Alzheimer's disease appears to disconnect areas of the brain that normally work together.NeurologyBrain and NervesQuickTime
200025.dcr200025r.gifThis animation illustrates and compares the severity of an ankle sprain (Type I, II, III).An ankle sprain occurs when the joint’s ligament is stretched or torn. Ligaments are bands or sheets of regular, tough fibrous tissue that connect bones together. Symptoms of an ankle sprain include swelling and discoloration near the affected area. Ankle sprains may be classified as follows:
• Type I sprain – ligaments stretched
• Type II sprain – ligaments slightly torn
• Type III sprain – ligaments completely torn
Treatment for a Type I sprain should include rest, ice, compression and immobilization, and elevation of the affected area. This is easy to remember if you think of the acronym RICE. If you suspect a ligament is torn or completely severed, see your medical care professional for treatment.
OrthopedicsBones and JointsShockwave 200035.mov200035r.gifThis animation shows the cardiac conduction system and the arrhythmias of a fast and slow beating heart.A change in the heart's normal electrical conduction system can result in an arrhythmia or irregular heartbeat. An arrhythmia can be an abnormally slow heartbeat, or an abnormally fast heartbeat. In some cases, it can be fatal.CardiologyHearts and VesselsQuickTime
200034.mov200034r.gifAtherosclerosis is a disease in which fatty material is deposited on the wall of an artery.Atherosclerosis is a disease in which fatty material is deposited on the wall of an artery. Normally the walls of an artery are smooth, allowing blood to flow unimpeded.
However, if damage occurs to inner lining, fat, cholesterol, platelets and other substances may accumulate at a damaged section of the arterial wall. Eventually, the tissue builds-up and a plaque if formed, narrowing the lumen of the artery. Where the narrowing is severe, there is a risk that the vessel can become blocked completely if a thrombus forms in the diseased segment.CardiologyHearts and VesselsQuickTime
200036.mov200036r.gifThis animation illustrates the location of basal ganglia in the brain. Injury to the basal ganglia may result in athetosis (constant writhing movements of the body).Athetosis, or constant writhing movements, is often caused by injury to deeply situated structures with the brain called basal ganglia.
NeurologyBrain and NervesQuickTime
200037.mov200037r.gifThis animation shows the use of balloon angioplasty to open a narrowed coronary artery lumen caused by deposits of plaque.Angioplasty is a procedure to open narrowed or blocked arteries caused by deposits of plaque. If the blockage is not major, the problem may be corrected by inflating the balloon several times to compact the plaque against the arterial wall, widening the passage for the blood to flow through. Typically, a device called a stent is placed within the coronary artery to keep the vessel open.CardiologyHearts and VesselsQuickTime
200038.mov200038r.gifThis animation shows the neurological control of normal bladder function.When the bladder fills with urine, sensory nerves send impulses to the brain indicating that the bladder is full. The sensory nerves connect with other nerves in the spinal cord to relay this information. In turn, the brain sends impulses back to the bladder instructing the bladder to empty its contents.Neurology,UrologyUrinary SystemQuickTime
200007.dcr200007r.gifThis animation shows the eye’s response to invading foreign substances, resulting in blinking and the lacrimal gland’s production of tears which then pass into the nose through tear ducts.The nervous system enables a person to blink to prevent harmful substances from getting in the eyes. During the normal course of a day, a person blinks an average of 15 times a minute to keep the eyes healthy. The lacrimal gland provides lubricating fluid for the eyes. The eyelid moves fluid from the lacrimal gland and across the eye. Blinking also provides the eyes with protection from foreign objects.
When the eye becomes irritated, the lacrimal gland produces extra tears to wash out impurities. Excess fluid drains through the tear ducts and into the nasal cavity. An abundance of tears draining through the nasal cavity may cause the nose to run and a person to sniffle.
Eyes and VisionBrain and NervesShockwave 200077.dcr200077r.gifThis animation depicts the process of blood clotting in an enlarged view of a small artery. Cells shown include red blood cells, platelets, fibrin, and clotting factors.The body contains a natural process to stop bleeding from minor cuts in a matter of several minutes. When a small artery is cut, the collagen fibers in its tissue are exposed, which signals clotting process to begin. As platelets begin to adhere to the cut edges, they release chemicals to attract even more platelets. Eventually a platelet plug is formed, and the external bleeding stops. Clotting factors in the blood cause strands of blood-borne material, called fibrin, to stick together and seal the inside of the wound. Eventually, the cut blood vessel heals, and the blood clot dissolves after several days.CardiologyHearts and VesselsShockwave
200078.dcr200078r.gifThis animation shows the cycle of blood circulation through the heart, arteries, veins, and lungs within the body.As the heart pumps, the arteries carry oxygen-rich blood (shown in red) away from the heart and toward the body’s tissues and vital organs. These include the brain, liver, kidneys, stomach, and muscles, including the heart muscle itself. At the same time, the veins carry oxygen-poor blood (shown in blue) from the tissues back toward the heart. From there, it passes to the lungs to receive more oxygen. This cycle repeats itself when oxygen-rich blood returns to the heart from the lungs, which pumps it throughout the body.CardiologyHearts and VesselsShockwave
200079.dcr200079r.gifThis animation defines normal blood pressure and the measurement of systole and diastole. Structures shown include a front-view of the heart beating, a cut-view of the heart beating, and blood flowing through a small artery.Normal blood pressure is important for proper blood flow to the body’s organs and tissues. Blood pressure moves from high pressure near the heart to low pressure away from the heart. The force of the blood on the walls of the arteries is called blood pressure. Blood pressure is measured both as the heart contracts, which is called systole, and as it relaxes, which is called diastole. Normal blood pressure is considered to be a systolic blood pressure of 120 millimeters of mercury a diastolic pressure of 80 millimeters of mercury (stated as "120 over 80"). If an individual were to have a consistent blood pressure reading of 140 over 90, he would be evaluated for having high blood pressure. If left untreated, high blood pressure can damage important organs, such as the brain and kidneys as well as lead to a stroke.CardiologyHearts and VesselsShockwave
200039.mov200039r.gifThis animation shows one method in which a severe wrist fracture is treated by inserting a bone graft from the hip followed by fixation with a metal plate and screws.If a bone fracture is severe, a bone graft may be used to help speed the healing process. In this example, a metal plate is also used and fixated with screws. The plate and screws will be removed after the bone has healed.OrthopedicsBones and JointsQuickTime
200008.dcr200008r.gifThis animation highlights the major sections of the brain and explains their primary functions.The brain is composed of more than a thousand million neurons. Specific groups of them, working in concert, provide us with the capacity to reason, to experience feelings, and to understand the world. They also give us the capacity to remember numerous pieces of information.
The 3 major components of the brain are the cerebrum, cerebellum, and brain stem.
The cerebrum is divided into is left and right hemispheres, each composed of a frontal, temporal, parietal, and occipital lobes. The cerebral cortex (gray matter) is the outside portion of the cerebrum and provides us with functions associated with conscious thought. The grooves and folds increase the cerebrum’s surface area, allowing us to have a tremendous amount of gray matter inside of the skull. Deep to the gray matter is the cerebral "white matter". The white matter provides for the communication between the cortex and lower central nervous system centers.
The cerebellum is located near the base of the head. It creates automatic programs so we can make complex movements without thinking.
The brain stem connects the brain with the spinal cord and is composed of 3 structures: the midbrain, pons, and medulla oblongata. The brain stem provides us with automatic functions that are necessary for survival.
NeurologyBrain and NervesShockwave 200041.mov200041r.gifThis animation shows a breast reduction (lift) procedure.In a breast lift or breast reduction procedure, incisions are made to accommodate a higher position for the areola and nipple, as well as to remove excess skin and breast tissue. Stitches usually follow the circumference of the areola, the natural lower crease of the breast, and a vertical line extending between the areola and lower crease.SurgeryReproductive System,SkinQuickTime
200020.dcr200020r.gifThis animation illustrates the major structures of the respiratory system and shows the mechanism of breathing (respiration).The two lungs are the primary organs of the respiratory system. Other components of the respiratory system conduct air to the lungs, such as the trachea (windpipe) which branches into smaller structures called bronchi.
The process of breathing (respiration) is divided into two distinct phases, inspiration (inhalation) and expiration (exhalation). During inspiration, the diaphragm contracts and pulls downward while the muscles between the ribs contract and pull upward. This increases the size of the thoracic cavity and decreases the pressure inside. As a result, air rushes in and fills the lungs.
During expiration, the diaphragm relaxes, and the volume of the thoracic cavity decreases, while the pressure within it increases. As a result, the lungs contract and air is forced out.
Allergies and Asthma,Ear, Nose and Throat (ENT)Lungs and BreathingShockwave 200043.mov200043r.gifThis animation shows the formation of a bunion.Bunions are usually caused by prolonged pressure put on the feet that compresses the big toe and pushes it toward the second toe. Over time, the condition may become painful as extra bone grows where the base of the big toe meets the foot.OrthopedicsBones and JointsQuickTime
200044.mov200044r.gifFrom a top view of the voice box (larynx) and vocal cords, this animation shows the formation of a malignant tumor on the right vocal cord.Malignant tumors of the vocal cords are typically caused by tobacco use.Cancer (Oncology)Lungs and BreathingQuickTime
200080.dcr200080r.gifThis animation illustrates the cardiac conduction system, a group of specialized muscle cells that signal the rest of the heart to contract. An ECG tracing is shown in tandem with a normal heart beat.The cardiac conduction system is a group of specialized cardiac muscle cells in the walls of the heart that send signals to the heart muscle causing it to contract. The main components of the cardiac conduction system are the SA node, AV node, bundle of HIS, bundle branches, and Purkinje fibers. The SA node (anatomical pacemaker) starts the sequence by causing the atrial muscles to contract. From there, the signal travels to the AV node, through the bundle of HIS, down the bundle branches, and through the Purkinje fibers, causing the ventricles to contract. This signal creates an electrical current that can be seen on a graph called an Electrocardiogram (EKG or ECG). Doctors use an EKG to monitor the cardiac conduction system’s electrical activity in the heart.CardiologyHearts and VesselsShockwave
200045.mov200045r.gifThis animation shows a catheter being inserted into the heart where alcohol is injected causing the swollen ventricle wall to shrink.In this case of cardiomyopathy, part of the septum dividing the ventricles, is interfering with the normal emptying of the left ventricle. This is one variety of the condition called hypertrophic obstructive cardiomyopathy (HOCM). A catheter is introduced into the heart and through it, concentrated alcohol is applied to the abnormal area, shrinking it, allowing the heart to function normally.CardiologyHearts and VesselsQuickTime
200081.dcr200081r.gifThis animation displays a normal heart beating. Also shown are red blood cells traveling through an enlarged cut-section of a small artery and the percentage of the blood’s components.The cardiovascular system is composed of the heart and the network of arteries, veins, and capillaries that transport blood throughout the body. The average adult male has between 5 to 6 liters of blood or blood volume, while the average adult female has between 4 to 5 liters. The blood carries oxygen and essential nutrients to all of the living cells in the body, and also carries waste products from the tissues to the systems of the body through which they are eliminated.
Most of the blood is made up of a watery, protein-laden fluid called plasma. A little less than half of this blood volume is composed of red and white blood cells, and other solid elements called platelets.CardiologyHearts and VesselsShockwave
200046.mov200046r.gifThis animations depicts how a cataract is seen in the eye.Cataracts may develop with advancing age or in response to diseases such as diabetes. A cataract appears as a cloudy area in the lens.Eyes and VisionBrain and NervesQuickTime
200110.dcr200110r.gifThis animation traces the growth and migration of a fertilized egg cell through the fallopian tubes to the uterine lining. Enlarged views show the action of cilia in the fallopian tube transporting the egg and its implantation into the uterine lining.During the first 12 hours after conception, the fertilized egg cell remains a single cell. After approximately 30 hours, it divides from 1 cell into 2 and 15 hours later, the 2 cells divide into 4. And at the end of 3 days, the fertilized egg cell has become a berry-like structure made up of 16 cells. This structure is called a morula, which is Latin for mulberry.
The cells continue to divide 8 or 9 days following conception into a blastocyst. Although it is only the size of a pinhead, the blastocyst is composed of hundreds of cells. The blastocyst is slowly carried by tiny hair-like projections in the fallopian tube called cilia toward the uterus. During the critically important process of implantation, it must attach itself to the uterine lining where it will be able to get nourishment from the mother’s blood supply. If the blastocyst is unable to attach, the pregnancy will fail to survive.OB/GYN,PediatricsReproductive SystemShockwave
200047.mov200047r.gifThis animation shows a cerebral aneurysm growing and rupturing filling the brain with blood.The tissue of the brain is supplied by a network of cerebral arteries. If the wall of a cerebral artery becomes weakened, a portion of the wall may balloon out forming an aneurysm. A cerebral aneurysm may enlarge until is bursts, sending blood throughout the spaces in or surrounding the brain.CardiologyHearts and VesselsQuickTime
200130.dcr200130r.gifThis interactive animation shows the process of cervical dilation during labor.Click and drag the slider bar to see the various stages of cervical dilation between 0 and 10 cm.OB/GYNReproductive SystemShockwave
200111.dcr200111r.gifThis animation describes and depicts the common reasons for having a cesarean section delivery. The location of an epideral application is shown in a side view followed by a Cesarean section delivery illustrated in both side and front views.Although Cesarean (C-sections) are relatively safe surgical procedures, they should only be performed in appropriate medical circumstances. Some of the most common reasons for a Cesarean are:
• If the baby is in a feet first (breech) position
• If the baby is in a shoulder first (transverse) position
• If the baby’s head is too large to fit through the birth canal
• If labor is prolonged and the mother’s cervix will not dilate to 10 centimeters
• If the mother has placenta previa, where the placenta is blocking the birth canal
• If there are signs of fetal distress which is when the fetus is in danger because of decreased oxygen flow to the fetus
Some common causes of fetal distress are:
• Compression of the umbilical cord
• Compression of major blood vessels in the mother’s abdomen because of her birthing position
• Maternal illness due to hypertension, anemia, or heart disease
Like many surgical procedures, Cesarean sections require anesthesia. Usually, the mother is given an epidural or a spinal block. Both of these will numb the lower body, but the mother will remain awake. If the baby has to be delivered quickly, as in an emergency, the mother may be given a general anesthetic, which will make her fall asleep.
During the surgery, an incision is made in the lower abdomen followed by an incision made in the uterus. There is no pain associated with either of these incisions because of the anesthesia. Once the uterus is open, the doctor will let the amniotic fluid drain from the amniotic sac. Then the baby is carefully eased through the incision and out into the world. The procedure usually lasts about ten minutes.
Afterward, the physician delivers the placenta and stitches up the incisions in the uterus and abdominal wall. Usually, the mother is allowed to leave the hospital within a week, barring complications.OB/GYN,Pediatrics,SurgeryReproductive SystemShockwave
200098.dcr200098r.gifThis animation shows an enlarged view of a section of skin, highlighting its layers and various structures.Skin is the body’s largest organ. About six pounds of skin cover eighteen square feet on an average adult.
The top layer of skin is called the epidermis. It protects the underlying skin layers from the outside environment and contains cells that make keratin, a substance that waterproofs and strengthens the skin. The epidermis also has cells that contain melanin, the dark pigment that gives skin its color. Other cells in the epidermis allow us to feel the sensation of touch and provide the body with immunity against foreign invaders like germs and bacteria.
The very bottom layer of the skin is the hypodermis. It contains the fat cells, or adipose tissue, that insulate the body and help it conserve heat. The layer between the epidermis and the hypodermis is the dermis. It contains the cells that give skin strength, support, and flexibility. As a person ages, the cells in the dermis lose their strength and flexibility, causing the skin to lose its youthful appearance.
Located in the dermis are sensory receptors. They allow the body to receive stimulation from the outside environment and experience pressure, pain, and temperature. Small blood vessels provide the skin with nutrients, and remove its waste products.
Sebaceous glands produce the oil in the skin, which keeps it from drying out. The oil from the sebaceous glands also helps to soften hair and kill bacteria that get in the skin’s pores. These oil glands are all over the body, except on the palms of the hands and the soles of the feet.DermatologySkinShockwave
200016.dcr200016r.gifThis animation shows the process of conception in which a sperm unites with an egg cell to form a fertilized egg.During intercourse, sperm are released into the vagina near the cervix, swim through the uterus and travel up the fallopian tubes. Sperm are composed of 3 parts: a head, a middle section, and a tail. The tail propels the sperm, which is powered by energy cells stored in the middle section. The head of the sperm contains the man’s genetic material and an enzyme-filled acrosomal cap needed to help the sperm penetrate through the outer membrane of the egg.
As an egg released by an ovary travels through a fallopian tube, it may encounter hundreds of sperm that have survived to reach this point in their journey. Eventually, one sperm may succeed in breaking through the egg’s outer membrane.
After penetrating the egg’s outer membrane, the sperm releases its nucleus, which unites with the nucleus from the egg. Fertilization or conception occurs when the sperm fuses with the egg to form a fertilized egg (zygote).
OB/GYN,UrologyReproductive SystemShockwave 200146.dcr200146r.gifThis interactive animation takes you on a journey through the female reproductive system to see the processes of ovulation, fertilization and implantation of a fertilized egg (zygote).Click a circle in the "Navigation" box to travel to a particular section of the female reproductive system. At each section, select the "Click here to play animation" to see an action occur that leads to the successful conception of a fertilized egg.OB/GYN,PediatricsReproductive SystemShockwave
200112.dcr200112r.gifThis animation shows the process in which an egg cell is fertilized by a sperm cell to form a fertilized egg (zygote).During sexual intercourse, sperm are released into the vagina near the cervix, which is the entrance to the uterus. The sperm travel through the cervix, into uterus and up the fallopian tubes.
After being release from an ovary, the egg cell moves through the fallopian tube by tiny cilia that line the tube’s walls. The egg cell only survives for approximately 24 hours after ovulation. Of the millions of sperm that are released into the naturally acid environment of the woman’s reproductive tract, relatively few will survive to encounter the egg cell.
When one of the sperm cells finally succeeds in breaking through the egg cell's outer membrane, the egg cell forms a protective barrier preventing other sperm cells from entering. This ensures that only one sperm cell fertilizes the egg cell.
Next, the sperm cell releases its nucleus containing the man’s chromosomes. After several hours, it unites with the nucleus of the egg cell, which contains the woman’s chromosomes. When the two nuclei fuse, their genetic material combines together to create a fertilized egg cell which is called a zygote.
OB/GYN,PediatricsReproductive SystemShockwave
200048.mov200048r.gifIn a microscopic view, this animations shows the conception of identical (maternal) twins.Millions of sperm are released during a single ejaculation. Their tails propel on their journey to encounter the single egg cell. Of the millions of sperm, only a few will survive to reach the egg and just one will penetrate the egg cell’s wall to combine it’s genetic material with that of the egg in the process called fertilization. If during the first week of cell division, the fertilized egg cell, or zygote, divides into 2 zygotes, identical twins will form. Each developing embryo contains the same genetic material as the other.OB/GYNReproductive SystemQuickTime
200049.mov200049r.gifThis animations shows the head receiving two impacts. One on the front, and one on the side from a boxing glove.In a severe impact to the head, the brain moves and hits the skull causing injury. During a boxing match, the brain moves from side to side after the impact of a punch. Following a concussion head injury, confusion and disorientation due to temporary distortion of the brain may result.NeurologyBrain and NervesQuickTime
200050.mov200050r.gifThis animation shows corneal infections resulting from corneal injury.Injury or infection of the cornea, the transparent front window of the eye, can lead to serious visual impairment.Eyes and VisionBrain and NervesQuickTime
200138.dcr200138r.gifThis animation shows a coronary artery bypass graft (CABG) procedure in which a portion of vein is grafted on the heart to reroute blood from a blocked section of a coronary artery.Coronary artery bypass graft surgery (CABG) is an invasive procedure that involves taking a section of vein from the leg and grafting it onto a location on the heart, which allows blood to bypass the blocked portion of the coronary artery.
The procedure begins with the surgeon making a cut in the leg and removing a section of vein. Both ends of the vein are tied-off in the leg and cut is closed. The chest is opened and the blood is rerouted through a heart-lung machine. The heart is then stopped.
The surgeon locates the blocked coronary artery and attaches the section of vein taken from the leg to the aorta and to the coronary artery below the blocked segment of the artery. The surgeon may do as many bypasses on as many blocked coronary arteries as the patient needs.
Once each bypass graft is placed, it is checked for leaks. Following this, the heart is restarted. Once the heart is beating again, the surgeon will remove its attachments to the heart-lung machine and sew the openings closed. Following this the chest is closed. A pacemaker may be inserted during the procedure to help control any heart rhythm problems the patient may have.
Cardiology,SurgeryHearts and VesselsShockwave 200082.dcr200082r.gifShown in an enlarged view of a damaged coronary artery is the build-up of plaque and restriction of blood flow, progressing to complete arterial blockage and heart muscle ischemia (heart attack). Anteriorly, a normal heart beating is also illustrated.The coronary arteries supply blood to the heart muscle itself. Damage to or blockage of a coronary artery can result in injury to the heart. Normally, blood flows through a coronary artery unimpeded. However, if the inner wall of a coronary artery becomes damaged, cholesterol plaque can build-up, progressively narrowing the available pathway through which blood can flow.
Clotted blood attempting to traverse the blood vessel may find it tortuous and too narrow for passage, and the artery may become completely constricted or blocked-off. The blocked artery results in a lack of oxygen, or ischemia, to the part of the heart muscle that the artery supplies. The result is a heart attack.CardiologyHearts and VesselsShockwave
200051.mov200051r.gifThis animation describes a series of cosmetic surgeries, including forehead lift, eyelid lift, and facelift.Facial cosmetic surgery may include a forehead lift. In this procedure, a hairline incision is made, the forehead skin is pulled-up and excess skin tissue is removed. In an eyelid lift (blepharoplasty), creases and wrinkles around the eyes can be minimized by removing excess fat and skin from the upper and lower eyelids. A facelift usually consists of an incision along or above the hairline and in front of the ears. Excess fat and skin is removed and facial muscles may be tightened.SurgerySkinQuickTime
200021.dcr200021r.gifThis animation shows the mechanism of coughing caused by an irritant entering the windpipe (larynx), resulting in its dislodgement. The steps of the coughing reflex are shown from a side view of the body in tandem with a top view of the vocal cords.Coughing is a sudden expulsion of air from the lungs through the epiglottis at an amazingly fast speed (estimated at 100 miles per hour). With such a strong force of air, coughing is the body’s mechanism for clearing the breathing passageways of unwanted irritants.
In order for a cough to occur, several events need to take place in sequence. First, the vocal cords open widely, allowing additional air to pass through into the lungs. Then the epiglottis closes off the windpipe (larynx), and simultaneously, the abdominal and rib muscles contract, increasing the pressure behind the epiglottis. With the increased pressure, the air is forcefully expelled, and creates a rushing sound as it moves very quickly past the vocal cords. The rushing air dislodges the irritant, making it possible to breathe comfortably again.
Allergies and Asthma,Ear, Nose and Throat (ENT)Lungs and BreathingShockwave 200052.mov200052r.gifThis animations depicts changes to the retina resulting from diabetes mellitus.Diabetes may affect the retina by causing the formation of whitish patches called exudates. Other indications may include tiny enlargements of the blood vessels resulting in microaneurysms and hemorrhages.Eyes and VisionBrain and NervesQuickTime
200142.dcr200142r.gifThis animation highlights the major parts of the digestive system and follows the breakdown of celery from consumption to excretion.Digestion is the process in which food is broken down into nutrients used by the body. Food passes from the mouth through the esophagus to the stomach. The stomach churns the food and breaks it down further with its contents of hydrochloric acid and an enzyme called pepsin.
The process of breaking food down in the stomach takes a few hours. From there, it goes to the duodenum where it is broken down further by digestive bile produced by the liver and stored in the gallbladder along with enzymes from the pancreas. Enzymes are chemicals that speed up the digestion of specific types of food. For example, the enzyme trypsin breaks down the protein in steak, lipase helps to break down fat, and lactase breaks down the sugar in milk.
Once everything is broken down, the small intestine absorbs the nutrients the body needs. From there the nutrients go into the bloodstream and to the liver, where poisons are removed. Undigested food and water continue through the small intestine and go into the large intestine, where water is reabsorbed. Finally, feces are eliminated through the rectum and anus.
GastroenterologyDigestive SystemShockwave 200139.dcr200139r.gifThis animation shows a Directional Coronary Atherectomy (DCA) procedure performed to remove the blockage from the coronary arteries by a tiny spinning cutter that slices away plaque lesions and stores them to be withdrawn.Directional Coronary Atherectomy (DCA) is a minimally invasive procedure to remove the blockage from the coronary arteries and allow more blood to flow to the heart muscle and ease the pain caused by blockages.
The procedure begins with the doctor injecting some local anesthesia into the groin area and putting a needle into the femoral artery, the blood vessel that runs down the leg. A guide wire is placed through the needle and the needle is removed. An introducer is then placed over the guide wire, after which the wire is removed. A different sized guide wire is put in its place.
Next, a long narrow tube called a diagnostic catheter is advanced through the introducer over the guide wire, into the blood vessel. This catheter is then guided to the aorta and the guide wire is removed. Once the catheter is placed in the opening or ostium of one the coronary arteries, the doctor injects dye and takes an x-ray.
If a treatable blockage is noted, the first catheter is exchanged for a guiding catheter. Once the guiding catheter is in place, a guide wire is advanced across the blockage, then a catheter designed for lesion cutting is advanced across the blockage site. A low-pressure balloon, which is attached to the catheter adjacent to the cutter, is inflated such that the lesion material is exposed to the cutter.
The cutter spins, cutting away pieces of the blockage. These lesion pieces are stored in a section of the catheter called a nosecone, and removed after the intervention is complete. Together with rotation of the catheter, the balloon can be deflated and re-inflated to cut the blockage in any direction, allowing for uniform debulking.
A device called a stent may be placed within the coronary artery to keep the vessel open. After the intervention is completed the doctor injects contrast media and takes an x-ray to check for any change in the arteries. Following this, the catheter is removed and the procedure is completed.
Cardiology,SurgeryHearts and VesselsShockwave 200114.dcr200114r.gifThis animation shows the signs of the first phase of labor (early labor).After the membranes rupture and the water breaks, a woman may begin to experience the first phase of labor (early labor). The average time of early labor is extremely variable, lasting anywhere from 2 to 6 hours. In rare cases, it can last up to 24 hours.
During this time, the pressure of repeated regular contractions causes the cervix, which had been closed when labor began, to open up to a diameter of 3 centimeters while becoming much thinner.
Various techniques can be used to help alleviate the discomfort a woman may experience during the first phase of labor such as back-rubs and breathing exercises.OB/GYN,PediatricsReproductive SystemShockwave
200115.dcr200115r.gifThis animation depicts the maturation of egg cells within ovary and illustrates the role of hormones in menstruation and egg cell fertilization and implantation.All of the immature egg cells (oocytes) a woman will ever produce are stored in the ovaries by the time she is born. The average age that girls begin to menstruate is 12 years old. Each menstrual cycle occurs approximately every 28 days. During each cycle, hormonal messages from the brain cause the ovaries to develop a single mature egg cell for potential fertilization, even as other hormones instruct the uterine lining to thicken in preparation for nourishing the fertilized egg cell.
The cycle starts when a follicle grows within one of the ovaries. A follicle is composed of the developing egg cell and the support cells that surround and nourish it. On day 1 of the cycle, a small structure in the brain, the pituitary gland, releases two hormones, FSH and LH, both of which cause the follicle to begin growing.
Over the next 13 days, the growing follicle releases estrogen, a hormone that prepares the lining of the uterus to receive a fertilized egg cell. Meanwhile, the estrogen in the bloodstream causes the brain to release a surge of LH. In response to the LH surge, the follicle enlarges rapidly. On day 14, it ruptures and releases the egg cell in a process known as ovulation.
The ruptured follicle begins secreting the hormone progesterone, which also helps to prepare the uterine lining for a fertilized egg cell. The egg cell is swept into the fallopian tube entrance by its waving structures called fimbriae.
Once the egg cell is within the fallopian tube, it will either be fertilized by a sperm cell, or fertilization will fail to take place. If the egg cell is not fertilized within 24 hours after its release from the ovary, it will stop developing and will dissolve before reaching the uterus. The absence of a fertilized egg cell gradually causes a woman’s body to stop releasing the hormones that would otherwise prepare the uterus for the developing egg cell. In response, the uterus sheds its lining on days 24 through 28 during menstruation.
If a sperm does fertilize the egg cell, tiny hair-like cells called cilia will transport it towards the uterus. The fertilized egg now called a blastocyst, lodges in the uterine wall in a process called implantation to receive nourishment from the uterine lining. The remaining cells of the ruptured follicle in the ovary produce progesterone so that the uterine lining will stay rich in blood vessels, and the fertilized egg cell will survive.OB/GYN,PediatricsReproductive SystemShockwave
200017.dcr200017r.gifThis animation illustrates the development cycle of an egg in an ovary and the sequence of events to fertilization of the egg or not.A woman is born with all of the egg cells she will release throughout her lifetime. Starting at about age 12 through menopause, a woman’s reproductive cycle releases an egg about once a month.
Hormonal messages from the brain instruct the ovaries to develop several follicles in which a single dominant follicle in one of the ovaries will release an egg for fertilization. During this time, other hormones instruct the uterine lining to thicken in preparation for nourishing a fertilized egg.
There are several hormones that regulate the reproductive cycle. Follicle stimulating hormone (FSH) stimulates preparation of the egg for fertilization by instructing a follicle to begin dividing it’s genetic material (chromosomes).
The follicle then releases estrogen, the hormone that prepares the lining of the uterus to receive a fertilized egg. Increased levels of estrogen in the bloodstream cause a small structure in the brain, the pituitary gland, to stop releasing the hormone FSH, and to start releasing luteinizing hormone (LH).
LH causes the follicle to enlarge rapidly and to release its egg in a process known as ovulation. Once the egg is out of the follicle, the follicle begins secreting the hormone progesterone, which also helps to prepare the uterine lining for the fertilized egg. The remaining cells of the follicle shrink into a hormone producing mass of cells called a corpus luteum.
The egg is swept into the fallopian tube by its waving structures called fimbriae. Fertilization of the egg usually occurs in the fallopian tube. From there, it is transported to the uterus and implants itself in the uterine wall, where it is nourished by the uterine lining. In the ovary, the corpus luteum produces progesterone so that the egg can develop into a fetus.
If the egg is not fertilized within 24 hours after its release from the ovary, it stops developing and dissolves before reaching the uterus. The absence of a fertilized egg causes the body to stop releasing the hormones that prepare the uterus for implantation. In response, the uterus sheds its lining over a period of four to five days in a process known as menstruation.
OB/GYNReproductive SystemShockwave 200141.dcr200141r.gifAn electrocardiogram (ECG) enables the rhythm of the heart to be viewed in waveform. This interactive animation shows the ECG waveforms for normal sinus rhythm and various conditions of the heart.Click the waveform pull-down list to view various waveforms showing normal and pathological conditions of the heart.Cardiology,Fitness,NeurologyHearts and VesselsShockwave
200091.dcr200091r.gifThis animation illustrates the glands of the endocrine system, specifically enlarging the pituitary gland, thyroid gland, parathyroid glands, thymus, adrenal glands, and pancreas. A communication path within the neuroendocrine system is also shown.The endocrine system is primarily composed of glands that produce chemical messengers called hormones. Glands of the endocrine system include the pituitary gland, the thyroid gland, the parathyroid glands, the thymus, and the adrenal glands. Other glands are also included within the endocrine system since they contain endocrine tissue that secretes hormones such as the pancreas, ovaries and testes.
The endocrine and nervous systems work very closely together. The brain continuously sends instructions to the endocrine system, and in return receives feedback from the endocrine glands. Because of this intimate relationship, the nervous and endocrine systems are referred to as the neuroendocrine system.
The hypothalamus is known as the master switchboard because it’s the part of the brain that controls the endocrine system. The pituitary gland, which hangs by a thin stalk from the hypothalamus, is called the master gland of the body because it regulates the activity of the endocrine glands.
The hypothalamus detects the rising level of the target organ’s hormones then sends either hormonal or electrical messages to the pituitary gland. In response, the pituitary gland releases hormones, which travel through the bloodstream to a target endocrine gland, instructing it to stop producing its hormones.
The endocrine system constantly adjusts hormone levels so that the body can function normally. This process is called homeostasis.EndocrinologyHormonesShockwave
200030.dcr200030r.gifThis animation illustrates the prostate gland and its surrounding structures and shows the effects of benign prostatic hypertrophy (BPH).The prostate gland is located underneath the bladder and is about the size of a chestnut. Part of the urethra is encased within the prostate gland. As a man ages, the prostate typically enlarges in size in a process called benign hypertrophy (non-cancerous enlargement).
The enlarged prostate crowds its surrounding structures and may cause the urethra to narrow. The narrowed urethra results in several of the symptoms of benign prostatic hypertrophy (BPH). Symptoms may include a slowed or delayed start in urination, the need to urinate frequently during the night, difficulty in emptying the bladder, a strong, sudden urge to urinate, and incontinence. Less than half of all men with BPH have symptoms of the disease, or their symptoms are minor and do not restrict their life style.
BPH is a normal physiological process of aging and treatment options are available. The choice of the appropriate treatment is based on the severity of the symptoms, the extent to which they effect lifestyle, and the presence of other medical conditions. Men with BPH should consult with their physician yearly to monitor the progression of the symptoms and decide the best course of treatment as needed.UrologyUrinary SystemShockwave
200003.dcr200003r.gifThis animation illustrates the prostate gland and its surrounding structures and shows the effects of benign prostatic hypertrophy (BPH).The prostate gland is located underneath the bladder and is about the size of a chestnut. Part of the urethra is encased within the prostate gland. As a man ages, the prostate typically enlarges in size in a process called benign hypertrophy (non-cancerous enlargement).
The enlarged prostate crowds its surrounding structures and may cause the urethra to narrow. The narrowed urethra results in several of the symptoms of benign prostatic hypertrophy (BPH). Symptoms may include a slowed or delayed start in urination, the need to urinate frequently during the night, difficulty in emptying the bladder, a strong, sudden urge to urinate, and incontinence. Less than half of all men with BPH have symptoms of the disease, or their symptoms are minor and do not restrict their life style.
BPH is a normal physiological process of aging and treatment options are available. The choice of the appropriate treatment is based on the severity of the symptoms, the extent to which they effect lifestyle, and the presence of other medical conditions. Men with BPH should consult with their physician yearly to monitor the progression of the symptoms and decide the best course of treatment as needed.
Geriatrics,UrologyReproductive System,Urinary SystemShockwave 200053.mov200053r.gifThis animation shows the release of epinephrine and its effect of the heart.During periods of stress, such as preparing to run in a race, the brain signals the adrenal glands to produce epinephrine or "adrenaline". Epinephrine increases the rate in which the heart beats. The increased cardiac output supplies more oxygen to the muscles, putting the body a heightened state to react. As a longer term response to stress, cortisol is secreted by the adrenal glands, promoting the release of energy.CardiologyHearts and VesselsQuickTime
200104.dcr200104r.gifThis animation gives a general comparison between anaerobic exercise (lifting weights) and aerobic exercise (jogging).Weight lifting is a form of anaerobic exercise. It is very demanding, requiring a great deal of energy, which quickly depletes the body’s oxygen reserves. Sprinting and push-ups are other examples of anaerobic activities. They each create a situation called oxygen debt, which requires us to breathe deeply and rapidly in order to restore a proper oxygen level to the muscle cells.
If oxygen reserves become depleted while exercising, muscles convert a starch, called glycogen, into energy. This conversion process creates a waste product called lactic acid, which can be partly responsible for muscle soreness the next day.
Jogging is a form of aerobic exercise. Exercising over a long duration requires a steady level of energy for the body. If properly conditioned, the body will be able to supply adequate oxygen to meet its energy requirements during aerobic exercise and much less lactic acid will be formed in the muscles.Cardiology,FitnessMuscular SystemShockwave
200009.dcr200009r.gifThis animation shows the body’s response to a bee sting on the nose, giving a general description of the communication between the peripheral nervous system detecting the pain and the central nervous system issuing a reactive response.Pain provides the body with a protective mechanism, alerting it to potential or actual damage to the body’s tissues. In the example of a bee sting, the pain receptors in the skin detect tissue damage from the bee sting. Then, the peripheral nerves send a pain signal to the brain. The brain analyzes the pain signal. In turn, the brain delivers a message back to the muscles of the arm to react.NeurologyBrain and NervesShockwave
200129.dcr200129r.gifCreating a new life is nothing short of a miracle. With the fetal development interactive tool, you can get an insider's view of a baby in the making - from conception to term. You can watch the entire development, specify portions of the pregnancy, or freeze the frame on a specific week by dragging the slider bars back and forth.Click and drag a slider bar underneath an image window to see the process of embryonic and fetal development.Embryology,OB/GYN,PediatricsReproductive SystemShockwave
200117.dcr200117r.gifThis animation illustrates the development of a baby’s outer ear from its embryonic origins. Structures of a baby’s middle and inner ear are also shown from the front view.The ears begin their development during the fifth week of pregnancy. Ear formation starts from a few small bulges called branchial arches. Portions of the branchial arches form into structures called auricular hillocks. The auricular hillocks grow and join together to form the outer ears.
During the fifth month, the inner and middle parts of the ear develop, but won’t be completely finished until birth.
Ear, Nose and Throat (ENT),PediatricsReproductive SystemShockwave 200022.dcr200022r.gifThis animation illustrates the passage of air and exchange of oxygen and carbon dioxide within the lungs on both a gross and microscopic level.Air first enters the body through the mouth or nose, quickly moves to the pharynx (throat), passes through the larynx (voice box), enters the trachea, which branches into a left and right bronchus within the lungs and further divides into smaller and smaller branches called bronchioles. The smallest bronchioles end in tiny air sacs, called alveoli, which inflate during inhalation, and deflate during exhalation.
Gas exchange is the delivery of oxygen from the lungs to the bloodstream, and the elimination of carbon dioxide from the bloodstream to the lungs. It occurs in the lungs between the alveoli and a network of tiny blood vessels called capillaries, which are located in the walls of the alveoli.
The walls of the alveoli actually share a membrane with the capillaries in which oxygen and carbon dioxide to move freely between the respiratory system and the bloodstream. Oxygen molecules attach to red blood cells, which travel back to the heart. At the same time, the carbon dioxide molecules in the alveoli are blown out of the body with the next exhalation.
CardiologyHearts and Vessels,Lungs and BreathingShockwave 200055.mov200055r.gifThis animation shows the affects of untreated glaucoma.Glaucoma is the development of increased pressure within the eye. If left untreated, glaucoma may damage the optic nerve, resulting in visual impairment and eventually blindness.Eyes and VisionBrain and NervesQuickTime
200056.mov200056r.gifThis animation shows uric acid crystals moving to the big toe joint causing pain.Gout is caused by increased production of uric acid. Uric acid crystals travel and accumulate in the joints, especially in the feet and legs, causing great pain and swelling.UrologyUrinary SystemQuickTime
200010.dcr200010r.gifThrough a series of magnifications of the ear, this animation depicts the movement, amplification, translation, and interpretation of sound waves traveling through the ear’s three regions, ultimately becoming neural messages sent to the brain.The ear is divided into three regions: the outer ear, middle ear and inner ear.
When sound waves enter the ear canal, they cause the eardrum to vibrate. The vibration moves the three bones in the middle ear, called the ossicles. The ossicles are also known as the hammer (malleus), anvil (incus), and stirrup (stapes). These tiny bones transfer and amplify sound waves to the oval window, which is located behind the stirrup.
When the oval window vibrates, it moves fluid across a membrane inside the cochlea. The fluid causes the membrane to move. Specialized hair cells translate this movement into nerve impulses, which are sent to the brain through the vestibulocochlear nerve. The brain interprets the impulses as sound.
Ear, Nose and Throat (ENT)Brain and NervesShockwave 200057.mov200057r.gifThis animation shows the various structures of the ear and the process of hearing.As sound waves entering the ear, they travel through the outer ear, the external auditory canal, and strike the eardrum causing it to vibrate. The central part of the eardrum is connected to a small bone of the middle ear called the malleus (hammer). As the malleus vibrates, it transmits the sound vibrations to the other two small bones or ossicles of the middle ear, the incus and stapes. As the stapes moves, it pushes a structure called the oval window in and out. This action is passed onto the cochlea, which is a fluid-filled snail-like structure that contains the receptor organ for hearing. The cochlea contains the spiral organ of Corti, which is the receptor organ for hearing. It consists of tiny hair cells that translate the fluid vibration of sounds from its surrounding ducts into electrical impulses that are carried to the brain by sensory nerves. As the stapes rocks back and forth against the oval window, it transmits pressure waves of sound through the fluid of the cochlea, sending the organ of Corti in the cochlear duct into motion. The fibers near the cochlear apex resonate to lower frequency sound while fibers near the oval window response to higher frequency sound.Ear, Nose and Throat (ENT)Brain and NervesQuickTime
200058.mov200058r.gifThis animation shows the procedure of a heart bypass surgery.Heart bypass surgery begins with an incision made in the chest, with the breastbone cut exposing the heart. Next, a portion of the saphenous vein is harvested from the inside of the leg. Pieces of this great vein will be used to bypass the blocked arteries in the heart. The venous graft is sewn to the aorta and to the affected coronary artery past the blocked site. The internal mammary artery from the chest may also be used to bypass a clogged artery. Several arteries may be bypassed depending on the condition of the heart.CardiologyHearts and VesselsQuickTime
200118.dcr200118r.gifThis animation shows the development of the fetal heart from day 18 to day 57. A functional comparison is made between a fetal and newborn heart.The embryo’s heart is the first organ that forms. It is derived from two primitive heart tubes. Between days 18 to 30, the primitive heart tubes fuse together, bend and twist to form a simple version of the heart. About half way through this process, the heart starts to beat.
At 2 months, the heart bears a close resemblance to what it will look like after the baby’s born. The resemblance is only superficial since the inside of the heart is different in both form and function.
In a newborn’s heart, oxygen-poor blood from the body enters the right atrium, goes to the right ventricle where it is pumped to the lungs to become rich with oxygen. From the lungs, the blood flows back to the heart filling the left atrium then enters the left ventricle. The left ventricle pumps the oxygen rich blood through the aorta, which carries it to the rest of the newborn’s body.
The fetal heart has the same basic components as the newborn heart, but there are a couple important differences. Because the placenta is providing all of the oxygen the fetus requires, its lungs are not needed to perform this task. Much of the fetus’ blood is detoured away from the lungs through two openings or connections: the foramen ovale, which connects the right and left atria, and the ductus arteriosus, which connects the aorta and the pulmonary artery. These two important connections will remain open up until the time of birth.
Within thirty minutes after the baby’s first breath, the ductus arteriosus will completely close, and the flap of the foramen ovale will shut off like a valve. This happens because of an increase in pressure on the left side of the heart, and a decrease on the right side. These changes in the heart anatomy cause the blood to flow to the lungs, which will take over their lifelong job of supplying oxygen to the body.Cardiology,PediatricsHearts and VesselsShockwave
200083.dcr200083r.gifThis animation follows the passage of blood through the heart’s chambers and valves.The heart is a four-chambered organ with four main vessels, which either bring blood to or carry blood away from the heart. The four chambers of the heart are the right atrium, right ventricle, left atrium, and left ventricle.
The great vessels of the heart include:
• Superior and inferior vena cava (brings blood from the body to the right atrium)
• Pulmonary artery (transports blood from the right ventricle to the lungs)
• Aorta (the body’s largest artery, which transports oxygen-rich blood from the left ventricle to the rest of the body)
A series of one-way valves keep the blood flowing in one direction with every heartbeat. Blood first enters the heart into the right atrium then passes from the right atrium through the tricuspid valve and into the right ventricle. When the right ventricle contracts, the muscular force pushes blood through the pulmonary semilunar valve into the pulmonary artery.
Blood then travels to the lungs, where it receives oxygen. Next, it drains out of the lungs via the pulmonary veins, and travels to the left atrium. From the left atrium, the blood is forced through the bicuspid valve into the left ventricle. The left ventricle is the major muscular pump that sends the blood out to the body systems. When the left ventricle contracts, it forces the blood through the aortic semilunar valves and into the aorta. The aorta and its branches carry blood to all the tissues of the body.CardiologyHearts and VesselsShockwave
200087.dcr200087r.gifThis animation depicts how certain ingested foods can cause regurgitation of the stomach’s contents back into the esophagus resulting in the sensation of heartburn. The relationship between the location of the esophagus and heart is shown in a front view of the body.Heartburn is pain felt in the chest by a burning sensation in the esophagus, which is located close to where the heart is. At junction between the stomach and esophagus is the cardiac sphincter. This muscular sphincter acts as a valve that normally keeps food and stomach acid in the stomach and prevents the stomach’s contents from regurgitating back into the esophagus.
However, certain foods may affect the cardiac sphincter, making it less effective. The stomach produces hydrochloric acid to digest food. The stomach has a mucous lining that protects it from hydrochloric acid, but the esophagus does not. When food and stomach acid regurgitate back into the esophagus, a burning sensation is felt near the heart resulting in heartburn. Antacids may be used to relieve heartburn by making stomach juices less acidic, therefore reducing the burning feeling felt in the esophagus. If heartburn becomes frequent or prolonged, medical intervention may be necessary to correct the problem.GastroenterologyDigestive SystemShockwave
200059.mov200059r.gifThis animation shows displacement of an intervertebral disk (disk between the vertebrae).The disks between the vertebrae are liable to displacement when put under strain. Heavy lifting may produce forces which cause a lumbar intervertebral disk to move out of place ("slipped disk").OrthopedicsBones and JointsQuickTime
200092.dcr200092r.gifThis animation depicts the process of maintaining homeostasis in the body through hormonal negative feedback mechanisms. An analogy is made between thermostat temperature regulation in a home to the hormonal control of sugar levels within the bloodstream.Homeostasis is a state of balance inside the body, where the body systems work together to keep it functioning normally. The endocrine system keeps this internal balancing act going by releasing chemicals called hormones. The release of the hormones is controlled by negative feedback mechanisms.
A negative feedback mechanism works something like a thermostat in your home. A thermostat helps maintain a constant temperature, called the normal range. When the temperature rises beyond the normal range, the thermostat turns on the air conditioner. Eventually the air conditioner restores the temperature to the normal range. This process is called negative feedback. It starts with a normal range, goes beyond the normal range, and then back to normal again.
An example of how negative feedback works in the body can be demonstrated by the endocrine system’s controls over the amount of sugar in the bloodstream. Insulin is a hormone secreted by the pancreas that maintains a normal amount of sugar in the bloodstream. Shortly after eating a candy bar, tiny sugar molecules enter the bloodstream raising the blood sugar levels. In response, the pancreas secretes the insulin into the bloodstream. Now, the sugar molecules move out of the bloodstream and into the cells of the skeletal muscles, fat and liver. In turn, the blood sugar levels return to normal.EndocrinologyHormonesShockwave
200119.dcr200119r.gifThis animation shows the formation of a fetal face during the early weeks of development.The human face starts as a series of paired tissue mounds called branchial arches. During embryotic development, the face forms from the first branchial arch along with the area just above it.
At 28 days of development, the lower jaw has fused together from the branchial arches. The nostrils start to form by day 21 and the eyes appear on each side of the head. 2 days later, the nostrils move toward the center of the face and the ears begin to form.
At 35 days, the nostrils are closer together and more of the eyes can be seen. At 40 days, the eyelids have developed and the nose begins to take its form. At 48 days, the nasal swellings have joined in the center of the face and the eyes have moved to the front of the head.
3 weeks later, the fetal face takes on its human appearance. The face continues to develop more typical proportions right up until the time of birth.EmbryologySkinShockwave
200060.mov200060r.gifThis animation shows the effects of hypertension on a cerebral artery.If left untreated, hypertension can lead to the thickening of arterial walls causing its lumen, or blood passage way, to narrow in diameter. As a result, the heart must work harder to pump blood through the narrowed arterial openings. In addition, people with hypertension may be more susceptible to stroke.CardiologyHearts and VesselsQuickTime
200095.dcr200095r.gifThis animation shows an enlarged view of femoral bone marrow containing immature specialized white blood cells (lymphocytes) and depicts their maturation and migration into either B cell or T cell lymphocytes.The immune system is comprised of specialized white blood cells, called lymphocytes that adapt themselves to fight specific foreign invaders. These cells develop into two groups in the bone marrow.
From the bone marrow, one group of lymphocytes migrates to a gland called the thymus and become T lymphocytes or T cells. Within the thymus, the T cells mature under the influence of several hormones.
The T cells mature into several different types, including helper, killer and suppressor cells. When matured, the T cell types are ready to work together to directly attack foreign invaders, providing what physicians call cell-mediated immunity. This type of immunity can become deficient in persons with HIV, the virus that causes Aids, because HIV attacks and destroys helper T cells.
The other group of lymphocytes, B lymphocytes or B cells, mature and develop within the bone marrow itself. In that process, they achieve the ability to recognize specific foreign invaders. From the bone marrow, B cells migrate through the body fluids to the lymph nodes, spleen and blood. B lymphocytes provide the body with humoral immunity as they circulate in the fluids in search of specific foreign invaders to destroy.ImmunologyImmune SystemShockwave
200061.mov200061r.gifThis animations shows the process of Intracytoplasmic sperm injection (ICSI), a procedure used to fertilize an egg cell outside of the body.Intracytoplasmic sperm injection, or ICSI, is a form of in vitro fertilization in which fertilization occurs outside of the body. First, egg cells are harvested and transferred to a special media in a laboratory dish. Within a few hours, a single sperm is injected through a fine needle into the center of an egg cell to aid in the process of fertilization. If successful, the cell will divide and form the beginning stages of an embryo. If necessary, the DNA of a single cell from an embryo may be checked to ensure that various genetic disorders are not present. Typically, several egg cells are harvested and fertilized at the same time then inserted back into the uterus to increase the chances that one will implant and develop into a successful pregnancy.OB/GYNReproductive SystemQuickTime
200031.dcr200031r.gifThis animation begins with an front view of the urinary tract and continues with the formation of kidney stones shown in a cut-section of the kidney. Severities of kidney stones are depicted, demonstrating various degrees of urine obstruction.The urinary tract includes the kidneys, ureters, bladder and urethra. Within each kidney, urine flows from the outer cortex to the inner medulla. The renal pelvis is the funnel through which urine exits the kidney and enters the ureter.
As urine can become very concentrated as it passes through the kidneys. When the urine becomes too concentrated, calcium, uric acid salts and other chemicals dissolved in the urine can crystallize, forming a kidney stone (renal calculus).
Usually the calculus is the size of a small pebble. But ureters are very sensitive to being stretched, and when stones form and distend it, the stretching can be very painful. Often, people may not know they have kidney stones until they feel the painful symptoms resulting from a stone being stuck anywhere along the urinary tract. Fortunately, small stones typically passed out of the kidneys and through the ureters on their own without causing any problems.
However, stones can become more problematic when they block the flow of urine. A staghorn kidney stone may obstruct the entire kidney. Fortunately, these stones are the exception rather than the rule.
UrologyUrinary SystemShockwave 200108.dcr200108r.gifThis animation gives a cartooned comical view of birth through a vaginal delivery.When a baby is ready to be born, the mother starts to feel labor contractions. That means that her uterus starts squeezing and pushing so the baby can come out. It’s a tight fit, but it doesn’t hurt the baby during delivery.OB/GYN,PediatricsReproductive SystemShockwave
200105.dcr200105r.gifIllustrated for a child’s perspective, this animation depicts the growth of a baby within a uterus from the first month to the ninth month of pregnancy.At 1 month, the baby growing inside the mother’s uterus is very small. The baby is so small she could fit in the palm of your hand and is about the size of your thumbnail.
Over the next 9 months, the baby will grow more inside the uterus until she is ready to be born.
OB/GYN,PediatricsReproductive SystemShockwave 200106.dcr200106r.gifIllustrated for a child’s perspective, this cartooned animation explains the sperm’s role in determining if a baby will be a girl or a boy.To make a baby, a man’s sperm meets and joins with a woman’s egg cell inside her body. Inside the man’s sperm are a set of instructions that tell the baby to be a boy or a girl.
The instructions in the man’s sperm cell can either carry the letter "X" or the letter "Y". If the letter is an "X", it means the baby will be a girl. If the letter is a "Y", the baby will be a boy.
OB/GYN,PediatricsReproductive SystemShockwave 200109.dcr200109r.gifIllustrated for a child’s perspective, this cartooned animation explains how food and air are supplied from the mother to the baby through it's umbilical cord.When the baby is in the mother’s uterus, it can’t eat or breathe on its own, so it needs some help. The baby has a little tube that goes to its middle called the umbilical cord. The umbilical cord goes to the placenta, which connects to the mother’s uterus.
Here’s how it works. First, the food that the mother eats and air that she breathes get into her bloodstream as very tiny pieces called molecules.
These molecules, or tiny pieces of food and air, travel through the mother’s bloodstream to her placenta. From there, they go to the umbilical cord and into the baby’s body. That’s how the baby eats and breathes inside the uterus.
After a baby is born, the umbilical cord goes away. Guess what’s left? You’re belly button.
OB/GYN,PediatricsReproductive SystemShockwave 200107.dcr200107r.gifCreated for a child’s perspective, this cartooned animation illustrates the appearance and origin of a sperm cell and egg cell as well as the development of a baby within the uterus.Two things are needed to make a baby: a sperm cell and an egg cell. A man makes the sperm cell inside his body and a woman makes the egg cell inside her body.
Both the sperm cell and egg cell are very small. You would need a microscope to see them in real life. A microscope is like a magnifying glass, only much stronger.
When the sperm cell and the egg cell meet each other, they make a tiny baby that’s smaller than a grain of salt. The baby will grow inside a special place in woman’s body called the uterus. After about nine months, the baby will come out as a little boy or girl.
OB/GYN,PediatricsReproductive SystemShockwave 200062.mov200062r.gifA vibrating suction cannula is shown removing abdominal fat.A vibrating suction cannula, or flexible tube, is used in a liposuction procedure. The cannula is inserted through a small hole into the abdominal fat tissue to remove excess fat deposits.SurgerySkinQuickTime
200102.dcr200102r.gifThis animation shows an enlarged view of one lymph node filtering out micro-organisms from the fluid passing through.The lymphatic system is a complex network of thin vessels, valves, ducts, nodes, and organs. It helps to protect and maintain the fluid environment of the body by producing, filtering, and conveying lymph and by producing various blood cells.
Lymph nodes play an important part in the body’s defense against infection. The most common cause of swollen lymph nodes is infection, which might occur even if the infection is trivial or not. Afferent lymph vessels bring unfiltered fluids into the lymph node to be filtered while efferent vessels carry clean fluids away from the lymph node and to the cardiovascular system where it helps form the plasma in the blood.
Overall, lymph nodes work like a biological filtering system. When the body is invaded by foreign organisms, the painful swelling sometimes felt in the neck, armpits, groin, or tonsils comes from the microorganisms being trapped inside collections of lymph cells or nodes. Eventually, these organisms are destroyed and eliminated by cells that line the walls of the lymph nodes and the swelling and pain subside.ImmunologyLymphatic SystemShockwave
200103.dcr200103r.gifThis animation discusses and depicts several aspects of the lymphatic system including a microscopic view of lymph formation, edema, breast lymphatics and the spread of breast cancer.The lymphatic system is often referred to as the body’s "secondary circulatory system". The lymphatic system collects excess fluid in the body’s tissues and returns it to the bloodstream.
Lymph formation occurs at the microscopic level. During the exchange of fluid and molecules between the blood circulation and body tissues, blood capillaries may not reabsorb all of the fluid. Surrounding lymphatic capillaries absorb the excess fluid. The fluid is then filtered and transported back by the lymphatic system into large veins near the heart.
The lymphatic system can play a very worrisome role in the spread of breast cancer. Components of the lymphatic system called lymph nodes are distributed at specific locations throughout the body. There is also an extensive network of lymphatic vessels in every woman’s breast tissue, which is important in regulating the local fluid balance as well as in filtering out harmful substances.
The lymph vessels in the breast may inadvertently supply cancerous cells with access to a highway along which the cancerous cells can move to other parts of the body. This process is called metastasis and may result in the formation of a secondary cancer mass in a different location of the body. Regular breast self examinations can help to detect tumors earlier in their growth, hopefully before they spread quickly or metastasize.Cancer (Oncology),ImmunologyLymphatic SystemShockwave
200063.mov200063r.gifThis animation shows the process of macular degeneration in the eye.The macula is the part of the retina that distinguishes fine details at the center of the field of vision. Macular degeneration results from a partial breakdown of the insulating layer between the retina and the choroid layer of blood vessels behind the retina. Macular degeneration results in the loss of central vision only.Eyes and VisionBrain and NervesQuickTime
200132.dcr200132r.gifThis interactive animation shows the changes that occur during the menstrual cycle to hormone levels, body temperature, an ovary, and lining of the uterus.Click and drag the slider bar to see changes that occur during a normal 28 day menstrual cycle.OB/GYNReproductive SystemShockwave
200005.dcr200005r.gifThis animation discusses the four functions of muscle and displays the three different types of muscle tissue in external and microscopic views.Muscles perform four important body functions: maintain body posture, stabilize the joints, provide mobility, and generate heat that the body requires.
The body contains three types of muscle to perform these functions:
• Smooth muscle - involuntary muscle found in the walls of body organs; functions without conscious control
• Cardiac muscle - involuntary muscle found only in the walls of the heart; functions without conscious control
• Skeletal muscle - attaches to and covers the bony skeleton to provide movement of the body; the only type of muscle under voluntary or conscious control
Cardiology,FitnessMuscular SystemShockwave 200011.dcr200011r.gifThis animation provides a general overview of the nervous system and shows the process in which nerve impulses are transmitted.The nervous system is composed of two divisions, the central nervous system (CNS) and peripheral nervous system (PNS). The CNS contains the brain and the spinal cord and the PNS consists of thousands of nerves that connect the spinal cord to muscles and sensory receptors.
A peripheral nerve is composed of nerve bundles (fascicles) that contain hundreds of individual nerve fibers (neurons). Neurons consist of dendrites, axon, and cell body. The dendrites are the tree-like structures that receive signals from other neurons and from special sensory cells that sense the body’s surrounding environment. The cell body is the headquarters of the neuron and contains its genetic information in the form of DNA. The axon transmits signals away from the cell body to other neurons.
Many neurons are insulated like pieces of electrical wire. This insulation protects them and also allows their signals to move faster along the axon. Without this insulation, signals from the brain might never reach the outlying muscle groups in the limbs.
The operation of the nervous system depends on the flow of communication between neurons. For an electrical signal to travel between two neurons, it must first be converted to a chemical signal, which then crosses a space of about a millionth of an inch wide. The space is called a synapse, and the chemical signal is called a neurotransmitter.
Neurotransmitters allow the billions of neurons in the nervous system to communicate with one another, making the nervous system the master communication system of the body.
NeurologyBrain and NervesShockwave 200120.dcr200120r.gifThis animation shows the early formation of the nervous system.The most critical stage of development for the embryo’s nervous system is the third and fourth weeks of pregnancy.
On day 14, the embryo looks like a little disc. The first part of the nervous system that forms is an indentation called the neural groove. Over the next 7 days, the groove deepens as the cells around it form ridges called neural folds.
By day 27, the neural folds wrap around the neural groove and form the neural tube. The neural tube will further develop into the brain and spinal cord. Structures called somites form the vertebral column, or backbone. They also help form the ribs and the muscles of the neck, arms, and legs.
The embryo’s nervous system is particularly vulnerable during the early stage of development, so an expectant mother should be careful about avoiding any substances that could potentially harm it.Embryology,NeurologyBrain and NervesShockwave
200084.dcr200084r.gifThis animation shows an enlargement of a blood capillary with red blood cells traversing through it. A section of the artery is enlarged further to display the exchange of oxygen and carbon dioxide between a capillary and its surrounding tissue.Nutrient exchange is a continuous cycle, constantly supplying the body with oxygen and nutrients while removing carbon dioxide and metabolic waste.
Red blood cells are the cells in the blood that carry oxygen from the lungs to the body tissues through blood pumped by the heart. As they travel away from the heart, they traverse smaller and smaller arteries, finally arriving at the collections of microscopic blood vessels called capillaries. Capillaries contain a high concentration of oxygen and nutrients, while the surrounding tissues contain a lower concentration. Through a process called diffusion, these particles leave the capillaries and enter the body’s tissues.
Conversely, the body’s tissues contain high concentrations of carbon dioxide and metabolic waste, while the capillaries contain a lower concentration. Waste products diffuse from the tissues into the capillaries and from there are carried by the venous system back toward the heart. The waste products are eventually eliminated from the bloodstream through the urinary and respiratory systems.CardiologyHearts and VesselsShockwave
200026.dcr200026r.gifThis animation compares the a normal adult knee joint and a knee joint affected by osteoarthritis.Osteoarthritis is the most common form of arthritis and is associated with the aging process. Osteoarthritis is a chronic disease causing the deterioration of the cartilage within a joint.
For most people, the cause of osteoarthritis is unknown, but metabolic, genetic, chemical, and mechanical factors play a role in its development. Symptoms of osteoarthritis include loss of flexibility, limited movement, and pain and swelling within the joint. The condition results from injury to the cartilage, which normally absorbs stress and covers the bones, so they can move smoothly.
The cartilage of the affected joint is roughened and becomes worn down. As the disease progresses, the cartilage becomes completely worn down and the bone rubs on bone. Bony spurs usually develop around the margins of the joint.
Part of the pain results from these bone spurs, which can restrict the joint’s movement as well.
OrthopedicsBones and JointsShockwave 200027.dcr200027r.gifThis animation begins by showing a hip fracture due to osteoporosis (fracture in neck of the femur, anterior view). The bone then dissolves into a frontal section to compare the bony interior of a normal femur to that of an osteoporotic femur.Osteoporosis is a condition that leads to loss of bone mass. From the outside, osteoporotic bone is shaped like normal bone. However, the inside of the bones becomes more porous during the again process due to the loss of calcium and phosphate. The loss of these minerals makes the bones more prone to fracture even during routine activities, like walking, standing, or bathing. Often, a person will sustain a fracture before becoming aware of the presence of the disease.
Prevention is the best measure for treating osteoporosis by eating a recommended balanced diet including foods with sufficient amounts of calcium, phosphorous, and vitamin D. In addition, maintaining a regular exercise program as approved by your health care provider will help to keep the bones strong.
Various medications can be used as part of the treatment for osteoporosis and should be discussed thoroughly with your health care provider. OrthopedicsBones and JointsShockwave
200064.mov200064r.gifThis animations shows the process of ovulation (the release a single egg cell from an ovary).Ovulation occurs though a sequence of hormonal responses. Located deep within the brain, the pituitary gland releases the hormones FSH and LH, which travel through the blood stream to the ovaries. These hormones signal the development and release a single egg cell from one of the ovaries. The sweeping motion of the fimbriae draws the egg cell through a very small space in the open body cavity into the uterine, or fallopian, tube. The egg cell will either be fertilized by sperm or will dissolve if fertilization does not take place.Diabetes, Thyroid and Hormones,OB/GYNReproductive SystemQuickTime
200065.mov200065r.gifThis animations shows sporatic brain activity and a twitching hand that occur with Parkinson's disease, followed by treatment with dopamine stimulation.In Parkinson's disease, dopamine production becomes irregular and inadequate and nerve cells cannot properly transmit messages. This results in the loss of muscle function. By providing an even, adequate supply of medication that the body converts into dopamine, neurons are able to transmit messages and tremors improve.NeurologyBrain and NervesQuickTime
200140.dcr200140r.gifThis animation shows a Percutaneous Transluminal Coronary Angioplasty (PTCA) procedure to open up blocked coronary arteries by inflating a tiny balloon to compress the plaque against the walls of the artery, flattening it out so that blood can once again flow through the blood vessel freely.Percutaneous Transluminal Coronary Angioplasty (PTCA) is a minimally invasive procedure to open up blocked coronary arteries, allowing blood to circulate unobstructed to the heart muscle.
The procedure begins with the doctor injecting some local anesthesia into the groin area and putting a needle into the femoral artery, the blood vessel that runs down the leg. A guide wire is placed through the needle and the needle is removed. An introducer is then placed over the guide wire, after which the wire is removed. A different sized guide wire is put in its place.
Next, a long narrow tube called a diagnostic catheter is advanced through the introducer over the guide wire, into the blood vessel. This catheter is then guided to the aorta and the guide wire is removed. Once the catheter is placed in the opening or ostium of one the coronary arteries, the doctor injects dye and takes an x-ray.
If a treatable blockage is noted, the first catheter is exchanged for a guiding catheter. Once the guiding catheter is in place, a guide wire is advanced across the blockage, then a balloon catheter is advanced to the blockage site. The balloon is inflated for a few seconds to compress the blockage against the artery wall. Then the balloon is deflated.
The doctor may repeat this a few times, each time pumping up the balloon a little more to widen the passage for the blood to flow through. This treatment may be repeated at each blocked site in the coronary arteries. A device called a stent may be placed within the coronary artery to keep the vessel open. Once the compression has been performed, contrast media is injected and an x-ray is taken to check for any change in the arteries. Following this, the catheter is removed and the procedure is completed.
Cardiology,SurgeryHearts and VesselsShockwave 200088.dcr200088r.gifThis animation follows the processing of food through the digestive tract, focusing on the intestinal peristaltic movement (a series of wave-like muscle contractions that moves the food mixture down the digestive tract).Peristalsis is a series of wave-like muscle contractions that moves food to different processing stations in the digestive tract. The process of peristalsis begins in the esophagus when a bolus of food is swallowed. The strong wave-like motions of the smooth muscle in the esophagus carry the food to the stomach, where it is churned into a liquid mixture called chyme.
Next, peristalsis continues in the small intestine where it mixes and shifts the chyme back and forth, allowing nutrients to be absorbed into the bloodstream through the small intestine walls.
Peristalsis concludes in the large intestine where water from the undigested food material is absorbed into the bloodstream. Finally, the remaining waste products are excreted from the body through the rectum and anus.GastroenterologyDigestive SystemShockwave
200096.dcr200096r.gifThis animation shows the process of a macrophage ingesting a foreign substance.Macrophages are scavenger cells that can ingest dead tissue and foreign cells. Macrophages form tentacles called pseudopods to surround an invader. Once inside the macrophage, the invader is walled off and then digested and destroyed by a bag of digestive chemicals, or enzymes.ImmunologyImmune SystemShockwave
200093.dcr200093r.gifThis animation describes the regulation of the pituitary gland and the hormones it releases to regulate various organs and processes in the body.The pituitary gland is often referred to as the "master gland" of the body, since it regulates many activities of other endocrine glands. Located above the pituitary gland is the hypothalamus. The hypothalamus decides which hormones the pituitary should release by sending it either hormonal or electrical messages.
In response to hormonal messages from the hypothalamus, the pituitary gland releases the following hormones:
• GH (growth hormone) – increases size of muscle and bone
• THS (thyroid stimulating hormone) – stimulates the thyroid gland to release T3 and T4 to stimulate metabolism in other cells throughout the body
• FSH (follicle stimulating hormone) – stimulates ovarian follicle production in women; stimulates sperm production in men
• LH (luteinizing hormone) – stimulates ovaries to produce estrogen in women; stimulates sperm production in men
• Prolactin – stimulates breast tissue in nursing mothers to produce milk
• ACTH (adrenocorticotropic hormone) - causes the adrenal glands to produce important substances that have properties similar to steroids
In response to electrical messages from the hypothalamus, the pituitary gland releases the following hormones:
• ADH (antidiuretic hormone) - stimulates the kidneys to reabsorb fluid and produce less urine
• Oxytocin – initiates labor, uterine contractions and milk ejection in mothersEndocrinologyHormonesShockwave
200121.dcr200121r.gifThis animation illustrates the delivery of the placenta by strong uterine contractions and gentle abdominal pressure applied by a physician.The placenta provides the baby with nutrients and oxygen from the mother and carries away fetal waste. Following delivery, the uterus naturally contracts to push the placenta out of the uterus. In addition, the delivering practitioner will assist by gently pressing the abdomen to work the placenta free of the uterus.
Delivery of the placenta is typically painless and takes approximately 15 minutes.
Once the placenta is delivered, it is examined to see if the placental tissue is healthy and in one piece. At times, the placenta can break off and cause bleeding in the uterus. The placenta is commonly referred to as the afterbirth. Its successful delivery signals the end of the final stage of childbirth.OB/GYNReproductive SystemShockwave
200066.mov200066r.gifThis animation depicts hypertension caused by pre-eclampsia that adversely affects the fetus by causing constriction of the placental arteries.Hypertension caused by pre-eclampsia can adversely affect the fetus by causing constriction of the placental arteries. Arterial constriction may result in severe reduction in the blood flow to areas of the placenta. If the blood flow remains constricted, areas of the placenta may "die", putting the baby in distress.OB/GYNReproductive SystemQuickTime
200018.dcr200018r.gifThis animation illustrates the development cycle of an egg in an ovary and the sequence of events to fertilization of the egg or not.A woman is born with all of the egg cells she will release throughout her lifetime. Starting at about age 12 through menopause, a woman’s reproductive cycle releases an egg about once a month.
Hormonal messages from the brain instruct the ovaries to develop several follicles in which a single dominant follicle in one of the ovaries will release an egg for fertilization. During this time, other hormones instruct the uterine lining to thicken in preparation for nourishing a fertilized egg.
There are several hormones that regulate the reproductive cycle. Follicle stimulating hormone (FSH) stimulates preparation of the egg for fertilization by instructing a follicle to begin dividing it’s genetic material (chromosomes).
The follicle then releases estrogen, the hormone that prepares the lining of the uterus to receive a fertilized egg. Increased levels of estrogen in the bloodstream cause a small structure in the brain, the pituitary gland, to stop releasing the hormone FSH, and to start releasing luteinizing hormone (LH).
LH causes the follicle to enlarge rapidly and to release its egg in a process known as ovulation. Once the egg is out of the follicle, the follicle begins secreting the hormone progesterone, which also helps to prepare the uterine lining for the fertilized egg. The remaining cells of the follicle shrink into a hormone producing mass of cells called a corpus luteum.
The egg is swept into the fallopian tube by its waving structures called fimbriae. Fertilization of the egg usually occurs in the fallopian tube. From there, it is transported to the uterus and implants itself in the uterine wall, where it is nourished by the uterine lining. In the ovary, the corpus luteum produces progesterone so that the egg can develop into a fetus.
If the egg is not fertilized within 24 hours after its release from the ovary, it stops developing and dissolves before reaching the uterus. The absence of a fertilized egg causes the body to stop releasing the hormones that prepare the uterus for implantation. In response, the uterus sheds its lining over a period of four to five days in a process known as menstruation.
OB/GYN,PediatricsReproductive SystemShockwave 200028.dcr200028r.gifThis animation shows the process of red blood cell formation and the components that comprise blood.
Blood carries various substances that must be brought to one part of the body or another. Red blood cells are an important element of blood. Their job is to transport oxygen to the body’s tissues in exchange for carbon dioxide, which is carried to and eliminated by the lungs.
Red blood cells are formed in the red bone marrow of bones. Stem cells in the red bone marrow called hemocytoblasts give rise to all of the formed elements in blood. If a hemocytoblast commits to becoming a cell called a proerythroblast, it will develop into a new red blood cell.
The formation of a red blood cell from hemocytoblast takes about 2 days. The body makes about two million red blood cells every second.
Blood is made up of both cellular and liquid components. If a sample of blood is spun in a centrifuge, the formed elements and fluid matrix of blood can be separated from each other. Blood consists of 45% red blood cells, less than 1% white blood cells and platelets, and 55% plasma.
Cardiology,OrthopedicsBones and Joints,Hearts and VesselsShockwave 200012.dcr200012r.gifThis animation shows the body’s reflex response to a hot substance landing on the hand.The skeletal muscles are under voluntary (conscious) control most of the time. However, skeletal muscle movement can also by induced by involuntary reflexes.
Reflexes are involuntary reactions to a stimulus such as the burning of the hand. As soon as a hot substance contacts the hand, pain receptors in the skin send a signal to the spinal cord. In turn, the spinal cord sends a signal back to the arm muscles that instruct the hand to pull away. The arm flexed as it withdrew, which is known as a flexor (withdrawal) reflex. There are many other reflexes that protect the body as well.
If the body did not have the reflexes to withdraw quickly from a painful stimulus, we would be at risk for serious injury.
NeurologyBrain and NervesShockwave 200067.mov200067r.gifThis animation shows the process in which light is transformed by the retina as electical impulses that travel to the brain through the optic nerve.As light enters the eye, it strikes the cells receptor cells of the retina called the rods and cones. A chemical reaction results in the formation of electric impulses, which then travel to the brain through the optic nerve.Eyes and VisionBrain and NervesQuickTime
200068.mov200068r.gifThis animation shows a retinal detachment injury.Retinal detachments are associated with a tear or hole in the retina through which the internal fluids of the eye may leak, causing separation of the retina from underlying tissues.Eyes and VisionBrain and NervesQuickTime
200123.dcr200123r.gifIn a side view of the body with the baby in utero, the mucous plug (bloody show) is illustrated followed by the rupturing of the amniotic sac (water breaking), indicating the onset of labor.One of the first signs of labor starting is the appearance of a mucus plug, or what is sometimes called a "bloody show." The bloody show is the discharge of a small amount of pinkish mucus that formed the barrier between the uterus and vagina during pregnancy.
Shortly after the bloody show, the amniotic sac ruptures and amniotic fluid begins to trickle out of the uterus and vagina. For some women, it can actually gush out in a stream. The rupturing of the amniotic sac, which surrounds and protects the baby, is commonly referred to as the "water breaking."
The combination of contractions, the bloody show, and water breaking indicates the start of the first phase of labor.OB/GYNReproductive SystemShockwave
200013.dcr200013r.gifThis animation illustrates the various structures of the eye and how the shape of the eye affects vision (nearsightedness and farsightedness).The eye is the organ of sight and is shaped as a slightly irregular hollow sphere. Various structures in the eye enable it to translate light into recognizable images. Among these are the cornea, the lens, and the retina.
Light first passes through the cornea, a clear dome-like structure covering the iris, or colored part, of the eye. The cornea bends, or refracts, the light onto the lens. The light is then refracted a second time while passing through the lens, finally focusing on the retina. The retina is the light sensitive part of the eye. Impulses travel down the optic nerve to the occipital lobe of the brain, which then interprets the image in the correct perspective.
The shape of the eye is very important in keeping the things we see in focus. If the shape of the eye changes, it affects a person’s vision.
Normally, light is precisely focused onto the retina at a location called the focal point. A nearsighted eye is longer from front to back than a normal eye causing light to be focused in front of the retina instead of directly onto it. This makes it difficult to see objects that are far away. Glasses with concave lenses are used to correct nearsightedness. The concave lens focuses light back onto the focal point of the retina.
Farsightedness occurs when the length of the eye is too short. Light is focused at a point behind the retina, making it difficult to see objects that are up close. A convex lens is used to correct farsightedness because it directs the focal point back onto the retina.
Eyes and VisionBrain and NervesShockwave 200124.dcr200124r.gifThis animation illustrates the development of the external sex organs in a female and male fetus.A baby’s sex is determined at the time of conception. When a baby is conceived, the X or Y chromosome carried by the sperm cell fuses with the X chromosome in the egg cell. The chromosome combination determines whether the baby will be female or male. An XX combination means the baby will be a girl and XY means it will be a boy.
Even though gender is determined at conception, the fetus doesn’t develop its external sexual organs until the fourth month of pregnancy. At seven weeks after conception, the front of the fetus appears to be sexually indifferent, looking neither like a female or a male.
Over the next five weeks, the fetus begins producing hormones that cause its sex organs to grow into either female or male organs. This process is called sexual differentiation. If the fetus is female, it will produce hormones called estrogens. If the fetus is a male, it will produce hormones called androgens.
Hormones will instruct a common structure called the genital tubercle to either form the clitoris in the female or the penis in the male. The clitoris and penis are called sexual analogs because they originate from the same structure.
PediatricsReproductive SystemShockwave 200069.mov200069r.gifThis animation shows a dislocation of the shoulder joint.A shoulder dislocation usually occurs as a result of force to the joint. The bone is pushed out of the socket, which may cause damage to the surrounding ligaments, tendons, and nerves.OrthopedicsBones and JointsQuickTime
200006.dcr200006r.gifThis animation illustrates the organization of skeletal muscle, enlarging from a muscle belly up to its myofibrils. Simultaneously in side and front views, the actions of a leg muscle and its myofibrils are shown while performing leg extension exercises.Skeletal muscle is well-organized body tissue, composed in a complex array of smaller and smaller structures. Each skeletal muscle is composed of many units called muscle fascicles. The fascicles are bound together by a type of connective tissue called fascia.
Fascicles are composed of smaller organizational units called muscle fibers.
Smaller strands called myofibrils organize muscle fibers. The myofibrils move as skeletal muscle contracts. It is the interaction of the myofibrils as they slide and pull along side each other that gives skeletal muscle its functional ability to do work and move things.
Putting it all back together, myofibrils compose muscle fibers, muscle fibers make-up muscle fascicles, and muscle fascicles are bound together by fascia to compose skeletal muscle.
Fitness,OrthopedicsMuscular SystemShockwave 200029.dcr200029r.gifThis animation highlights the individual bones and groups of bones that comprise the skeletal system.The skeletal system consists of approximately 206 bones, providing the body with structure and support.
The skull has 8 cranial bones that protect the brain. The facial skeleton has 14 bones that provide a framework for the eye sockets, jaws, and teeth. The facial bones provide the framework for the various structures of the face including the overlying muscles, fat and skin.
The vertebral column is composed of 24 individual vertebrae, along with two sets of fused bones called the sacrum and coccyx. The vertebral column protects the spinal cord and provides support for the trunk of the body. 12 pairs of ribs form a protective cage for the heart, lungs, and other internal organs.
The shoulder joint is the most movable joint in the body and includes the shoulder blade (scapula) and collar bone (clavicle). The bones of the upper limb include the humerus, which connects the shoulder with the elbow, the ulna, the radius, the wrist bones or carpals, the hand bones or metacarpals, and the finger bones or phalanges.
A pair of hip bones forms the pelvic girdle. Each hip bone is comprised of 3 fused bones, the ilium, ischium, and pubis. The pelvic girdle connects with the thigh bone (femur) at the hip joint. The femur is the longest bone in the body and is important for bearing the body’s weight while standing.
The femur articulates with the shin bone (tibia) at the knee. The fibula does not bear weight, but several muscles attach to it. The kneecap (patella) is suspended within muscle tendons and glides over the femur and tibia when the knee bends. The foot bones, which include the tarsals, metatarsals, and phalanges, are organized into a series of arches that allow the feet to support the body’s weight.OrthopedicsBones and JointsShockwave
200099.dcr200099r.gifThis animation illustrates some common skin conditions such as moles, birthmarks, age spots, and warts.A few common skin conditions include moles, birthmarks, age spots, and warts.
Moles are colored spots on the skin, formed by cells containing the dark pigment, melanin. While generally harmless, some moles can change shape and color, or start bleeding and require immediate evaluation.
Some birthmarks are simply moles that are present at birth, called a pigmented birthmark. Others result from the rapid growth of blood vessels in a localized area, called red birthmarks.
When a person becomes older, they may develop age spots. Age spots are patches of increased pigmentation on the skin’s surface, like freckles.
Warts are benign, or non-cancerous, growths of skin caused by a virus.DermatologySkinShockwave
200014.dcr200014r.gifThis animation depicts the inhalation of air and scent molecules from a rose into an enlarged sagittal view of the nasal cavity. The smell receptors are magnified further to show their action of relaying a neural message of “scent” to the brain.As a person inhales, air and scent molecules move past the smell receptors in the nose. In turn, the smell receptors relay a signal to the brain. Smells can trigger memories and emotional responses.Ear, Nose and Throat (ENT)Brain and NervesShockwave
200023.dcr200023r.gifNormal, healthy lungs are compared to the lungs of a long-term smoker.
The lungs are the primary respiratory organs. They act as filters for the air the body breathes in and normally are a healthy pink color.
Filtering smoke from the air breathed in can do damage to the lung tissue as seen in a smoker’s lung. Over time, carbon molecules from inhaled smoke deposit in the lung tissue, giving it a blackened appearance.
Smoking can eventually lead to the formation of tumors and other serious lung diseases. Smoking has also been linked to diseases that affect the cardiovascular system, such as atherosclerosis, which can lead to a heart attack or stroke.
Cancer (Oncology),Cardiology,Ear, Nose and Throat (ENT)Lungs and BreathingShockwave 200024.dcr200024r.gifFrom a side view of the head and neck, this animation shows the structures involved in snoring. The common causes for snoring are also discussed
Snoring affects many of people during their sleep when the airway become partially blocked, forcing the lungs to inhale harder to compensate for the lack of air entering the body. The snoring sound results from the vibration the soft palate and the uvula.
Several factors are thought to cause snoring, including poor muscle tone, too much alcohol, heavy smoking, colds or allergies, obesity, and obstruction by enlarged adenoids and tonsils.
Usually, snoring is not an indication of an underlying disorder. However, people who snore and have quiet periods lasting more than 10 seconds may have some degree of sleep apnea.
Ear, Nose and Throat (ENT)Lungs and BreathingShockwave 200126.dcr200126r.gifThis animation highlights the structures of the male reproductive system and the pathway of ejaculate. A testicle is sectioned and enlarged to depict its internal anatomy, including a microscopic view of individual sperm.Sperm are produced, stored, and delivered by the male reproductive system. The male reproductive system includes the testes, urethra, vas deferens, prostate gland, seminal vesicle, and penis.
The testes contain coiled structures called seminiferous tubules, which are the sites of sperm production. They produce over 12 billion sperm per month. The epididymis lies on top of the seminiferous tubules. Immature sperm migrate from the seminiferous tubules to the epididymis to mature and be stored. The migration process usually takes about 20 days. Before intercourse, the penis fills with blood and becomes erect. With sufficient stimulation, the ejaculatory process begins.
The mature sperm travel from the epididymis through the vas deferens. The vas deferens is a narrow, muscular tube about 18 inches long. Its smooth muscle contractions propel the sperm forward. They arrive first at the ampulla, the widest part of the vas deferens, and then pass into the ejaculatory ducts. In the ejaculatory ducts, a liquid secretion from the seminal vesicles mixes with the sperm. Seminal fluid contains fructose sugar, which the sperm use as fuel as well as alkalines, which help to counteract the naturally acidic environment of the vagina and uterus providing the sperm a better chance for survival.
The liquid mixture is propelled forward through the ejaculatory ducts toward the urethra, passing first through the prostate gland, where milky prostatic fluid is added, forming the substance we call semen. The prostatic fluid helps the sperm swim faster, which is important for getting to the egg cell.
Finally, about a teaspoon of semen is ejected out (ejaculated) through the far end of the urethra at the end of the penis. From the time the sperm leave the man’s body