You should not use this medicine if you have had an allergic reaction to clarithromycin, erythromycin, or other macrolide antibiotics, or if you are also using cisapride (such as Propulsid®), pimozide (such as Orap®), astemizole, terfenadine (such as Seldane®), ergotamine or dihydroergotamine.
Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.
Swallow the extended-release tablet whole. Do not crush, break, or chew it.
Take the extended-release tablet (Biaxin® XL) with food or milk. The Biaxin® tablet and oral liquid can be taken with or without food.
Measure the oral liquid (Biaxin® Granules) with a marked measuring spoon or medicine cup. Shake the medicine well just before using. Use the oral liquid within 14 days after filling the prescription.
If a dose is missed:
If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
There are many other drugs that can interact with clarithromycin. These include terfenadine (such as Seldane®), astemizole (such as Hismanal®), cisapride (such as Propulsid®), pimozide (such as Orap®), carbamazepine, hexobarbital, phenytoin, valproate, colchicine, alfentanil, cilostazol, theophylline, rifabutin, zidovudine (such as Retrovir®), ritonavir (such as Norvir®), methylprednisolone, or anticoagulants or blood thinner like warfarin (such as Coumadin®).
Make sure your doctor knows if you are also taking ergotamine or dihydroergotamine, digoxin (such as Lanoxin®), quinidine (such as Cardioquin® or Quinaglute®), disopyramide (such as Norpace®), triazolam (such as Halcion®), alprazolam, midazolam, cyclosporine, tacrolimus, sildenafil (such as Viagra®), bromocriptine, or medicines to lower cholesterol (such as Lipitor®, Pravachol®, Zocor®).