You should not receive this medicine if you have had an allergic reaction to epinephrine, prilocaine, amide anesthetics or sulfite. You should not receive this medicine if you have a blood-iron disorder such as methemoglobinemia.
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
There are many other medicines that can interact with this medicine. Make sure your doctor knows about all other medicines you are using.
Make sure your doctor knows if you are using MAO inhibitors such as Eldepryl®, Marplan®, Nardil®, or Parnate®. Tell your doctor if you are using medicines for depression such as amitriptyline, imipramine, Norpramin®, or Vivactil®.
Make sure your doctor knows if you are using phenothiazines such as Compazine®, Phenergan®, Serentil®, or Thorazine®.
Make sure your doctor knows if you are pregnant or breastfeeding.
Make sure your doctor knows if you have asthma, heart disease, high blood pressure, liver disease, kidney disease or a blood problem called glucose-6-phosphate dehydrogenase deficiency (G6PD).
Make sure your doctor knows if you are allergic to other medicines.
This medicine will numb your lips, tongue, cheek, or mouth. Until you regain all the feeling, be careful that you do not injure the treated area. Avoid chewing food or drinking hot liquids until the sensations are back to normal.
Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.