You should not receive this medicine if you have had an allergic reaction to ibuprofen or other NSAID medicines, such as aspirin, naproxen, Advil®, Aleve®, Ecotrin®, or Motrin®. You should not receive this medicine if you have aspirin-sensitive asthma or have just had a coronary artery bypass graft (CABG), a type of heart surgery.
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using aspirin, a blood thinner (such as warfarin, Coumadin®), a steroid medicine (such as dexamethasone, prednisolone, prednisone, or Medrol®), or a diuretic or "water pill" (such as furosemide, hydrochlorothiazide [HCTZ], torsemide, Demadex®, or Lasix®).
Do not use any other NSAID medicine unless your doctor says it is okay. Some other NSAID medicines are naproxen, Advil®, Aleve®, Celebrex®, Ecotrin®, and Motrin®.
Make sure your doctor knows if you are also using lithium (Eskalith®), methotrexate (Rheumatrex®), or medicine to lower blood pressure (such as enalapril, lisinopril, Accupril®, Lotrel®, or Zestril®).
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
Make sure your doctor knows if you are breastfeeding or have kidney disease, liver disease, anemia, bleeding problems, high blood pressure, congestive heart failure (CHF), systemic lupus erythematosus (SLE), or a history of stomach ulcers or bleeding.
This medicine may increase your risk of having a heart attack or stroke. This is more likely to occur in people who already have heart disease. People who use this medicine for a long time might also have a higher risk.
This medicine might cause bleeding in your stomach or intestines. This is more likely to occur if you have had a stomach ulcer in the past, if you smoke or drink alcohol regularly, are over 60 years of age, are in poor health, or are using certain other medicines (such as steroids or a blood thinner).
Liver problems may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you are having more than one of these symptoms: abdominal pain or tenderness; clay-colored stools; dark urine; decreased appetite; fever; headache; itching; loss of appetite; nausea and vomiting; skin rash; swelling of the feet or lower legs; unusual tiredness or weakness; or yellow eyes or skin.
This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth after you get the injection.
Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loosening of the skin; red skin lesions; a severe skin rash or acne; sores or ulcers on the skin; or fever or chills while you are using this medicine.
Check with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after you receive this medicine. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).
Call your doctor right away if you have confusion, drowsiness, fever, a general feeling of illness, a headache, loss of appetite, nausea, stiff neck or back, or vomiting. These could be symptoms of a serious condition called meningitis.
Tell your doctor if you have unexplained weight gain or edema (fluid retention or body swelling) with this medicine.
Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.