You should not use this medicine if you have had an allergic reaction to isosorbide or similar medicines (such as nitroglycerin or Monokit®). You should not use this medicine if you are also using Viagra®.
Tablet, Long Acting Capsule, Long Acting Tablet, Chewable Tablet
Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
It is best to take this medicine on an empty stomach.
Use this medicine exactly as directed, or it will not work properly. Most people use this medicine for only part of each day.
Swallow the extended-release tabletor extended-release capsule whole. Do not break, crush, or chew it.
Chew the chewable tablet completely. Hold the medicine in your mouth for a about 2 minutes before you swallow it.
If you are using the sublingual tablet (under the tongue), sit down while taking this medicine. Wet the tablet with water or saliva. Place the tablet under your tongue and let it dissolve there. Do not chew, crush, or swallow the tablet whole. Avoid eating, drinking, or smoking while tablet is dissolving. If your chest pain lasts longer than 5 minutes, put a second tablet under your tongue. If the pain lasts another 5 minutes, use a third tablet. If your pain does not go away after the third dose, call your doctor and have someone take you to a hospital.
If a dose is missed:
If you miss a dose or forget to use your medicine, use it as soon as you can. If your next regular dose is less than 2 hours away, wait until then to use the medicine and skip the missed dose.
Do not use extra medicine to make up for a missed dose.
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using diuretics or "water pills" (such as furosemide, hydrochlorothiazide, Hyzaar®), or heart or blood pressure medicine (such as verapamil, Adalat®, Calan®, Cardizem®, Lotrel®, Plendil®, Procardia®, Tiazac®).
Do not drink alcohol while you are using this medicine.
Make sure your doctor knows if you are pregnant or breastfeeding, or if you have low blood pressure, congestive heart failure (CHF), an enlarged heart, or other heart problems.
Medicines that treat chest pain sometimes cause headaches. These headaches are a sign that the medicine is working. Do not stop taking the medicine or change the time you take it in order to avoid the headaches. You may take aspirin or Tylenol® to relieve the headache. If you have severe pain, talk with your doctor.
This medicine may make you dizzy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert. You may feel lightheaded when standing, so stand up slowly.
Do not stop using this medicine suddenly without asking your doctor. You may need to slowly decrease your dose before stopping it completely.