You should not use this medicine if you have ever had an allergic reaction to ketoconazole, miconazole (Monistat®), or fluconazole (Diflucan®). Ketoconazole should not be used with terfenadine (Seldane®), astemizole (Hismanal®), cisapride (Propulsid®), or triazolam (Halcion®).
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Certain drugs should not be used while using ketoconazole. Using these drugs can cause very serious medical problems, heart problems, or even death.
Make sure your doctor knows if you are also using antacids, Tagamet®, Pepcid®, Axid®, Zantac®, or Prilosec®.
Also, tell your doctor if you are using cyclosporine (Sandimmune®), digoxin (Lanoxin®), isoniazid (INH®), methylprednisolone, midazolam (Versed®), phenytoin (Dilantin®), rifampin (Rifadin®), tacrolimus (Prograf®), or warfarin (Coumadin®).
Your doctor may want to test your blood while you are using this medicine. Be sure to keep all appointments.