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Leucovorin (By mouth)

Introduction:

Leucovorin (loo-koe-VOE-rin)

Prevents and treats side effects caused by certain kinds of medicines such as methotrexate (an anti-cancer medicine) or pyrimethamine (used to treat infections).

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to leucovorin.

How to Use This Medicine:

Tablet

  • Your doctor will tell you how much medicine to take and how often. Make sure you understand your doctor's orders.
  • If you vomit right after you take this medicine, tell your doctor.

If a dose is missed:

  • This medicine needs to be given on a regular schedule. If you miss a dose, call your doctor for instructions.

How to Store and Dispose of This Medicine:

  • Store the tablets at room temperature, away from heat, moisture, and direct light.
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also taking fluorouracil, phenobarbital, phenytoin (Dilantin®), or primidone (Mysoline®).

Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • Before taking this medicine, make sure your doctor knows if you have anemia.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Wheezing or trouble breathing
  • Skin rash, itching, or hives
  • Swelling in the lips, face, or tongue
  • Reviewed last on: 1/4/2010
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