You should not use this medicine if you have had an allergic reaction to meclofenamate, aspirin, or other pain and arthritis medicines such as Motrin®, Indocin®, Naprosyn® or Aleve®, Tolectin®, or Clinoril®. The reaction may have included wheezing or trouble breathing, hives, rash, or swelling in the face.
Talk with your doctor before taking this medicine if you are pregnant, breastfeeding, or have heart disease, high blood pressure, liver or kidney disease, blood disorders, or ulcers or other stomach problems.
Ulcers and stomach bleeding are sometimes caused by this type of medicine. These problems can happen without warning signs. You may need to see your doctor for regular check-ups while being treated with this medicine.