You should not use this medicine if you have had an allergic reaction to promethazine, meperidine or to any phenothiazine medicine (such as Thorazine® or Mellaril®). You should not take this medicine if you have taken an MAO inhibitor medicine, such as Nardil®, Eldepryl®,or Parnate® in the past 14 days.
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Avoid drinking alcohol.
Make sure your doctor knows if you are taking any other medicine that could make you drowsy, such as sleeping pills, cold or allergy medicines, tranquilizers, muscle relaxants, antidepressants, or strong pain killers.