You should not use this medicine if you have had an allergic reaction to methoxsalen, or to other psoralen compounds. You should not use this medicine if you have melanoma, skin cancer, or if you have a disease with extreme sensitivity to sunlight (such as porphyria, lupus).
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are using medicines such as anthralin, coal tar, griseofulvin, or phenothiazines (Compazine®, Phenergan®).
Make sure your doctor knows if you are using a sulfa drug (such as trimethoprim/sulfamethoxazole, Bactrim®, Cotrim®, or Septra®). Tell your doctor if you also use nalidixic acid, or tetracyclines such as doxycycline, minocycline, Minocin®, or Vibramycin®.
Make sure your doctor knows if you are also using antiseptic soaps, diuretics (water pills) such as hydrochlorothiazide (Maxide®), or certain organic staining dyes such as methylene blue, toluidine blue, rose bengal, or methyl orange.
Do not use cosmetics or other skin care products on the treated skin areas.