You should not use this medicine if you have had an allergic reaction to morphine, codeine, hydrocodone, dihydrocodeine, oxycodone, or brands such as Tylox®, Tylenol® No. 3, Vicodin®. You should not use this medicine or if you have breathing problems, severe asthma, or a stomach problem known as paralytic ileus.
Your doctor will tell you how much of this medicine to take and how often. Do not take more medicine or take it more often than your doctor tells you to.
Measure the oral liquid medicine with a marked measuring spoon or medicine cup.
If you cannot swallow the capsule whole, you may open it and mix the medicine pellets with a small amount of applesauce, pudding, juice, or water. Swallow the mixture right away, without chewing or crushing the pellets.
You may take this medicine with food or milk if it upsets your stomach. Drink plenty of water and get plenty of exercise to avoid constipation.
If a dose is missed:
If you miss a dose or forget to take your medicine, take it as soon as you can. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using buprenorphine (Buprenex®), butorphanol (Stadol®), cyclosporine (Neoral®, Sandimmune®), dezocine (Dalgan®), esmolol (Brevibloc®), metformin (Glucophage®, Glucovance®), methohexital (Brevital®), nalbuphine (Nubain®), pentazocine (Talwin®), rifampin (Rifamate®, Rifater®), tramadol (Ultram®), diuretics ("water pills"), phenothiazines (such as Compazine®, Phenergan®, Serentil®, Thorazine®), or an MAO inhibitor (Eldepryl®, Marplan®, Nardil®, Parnate®).
Do not drink alcohol while you are using this medicine. Make sure your doctor knows if you are using any other medicine for pain relief, or any medicines that make you sleepy (such as sleeping pills, cold and allergy medicine, or sedatives).
Make sure your doctor knows if you are pregnant or breastfeeding, or if you have emphysema or other breathing problems, stomach problems or intestinal blockage, low blood pressure, seizures, Addison's disease, liver or kidney disease, pancreatitis, prostate disorders, thyroid disorders, problems with urination, or a history of depression, mental illness, alcoholism, head injury, or brain tumor.
This medicine may be habit-forming. If you feel that the medicine is not working as well, do not take more than your prescribed dose. Call your doctor for instructions.
Do not stop using this medicine suddenly without asking your doctor. You may need to slowly decrease your dose before stopping it completely.
This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
This medicine may cause constipation. This is more common if you use it for a long time. Ask your doctor if you should also use a laxative to prevent and treat constipation.