You should not use this medicine if you have had an allergic reaction to niacinamide (niacin). You may not be able to use this medicine if you have severe liver disease, ulcers, or if you have certain bleeding problems.
Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.Carefully follow your doctor's instructions about any special diet or exercise program.
It is best to take this medicine after your last meal of the day.
Swallow the extended-release tablet whole. Do not crush, break, or chew it.
If a dose is missed:
If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are using another medicine to lower cholesterol such as lovastatin, Lescol®, Lipitor®, Pravachol®, or Zocor®. Tell your doctor if you are using aspirin, vitamin supplements, or a nitrate medicine such as nitroglycerin or isosorbide.
Make sure your doctor knows if you are also using medicine to lower blood pressure. Some blood pressure medicines are atenolol, diltiazem, nifedipine, propranolol, verapamil, Cartia®, Coreg®, Lotrel®, Norvasc®, Plendil®, Tiazac®, and Toprol®.
Make sure your doctor knows if you drink alcohol on a daily or regular basis.
Make sure your doctor knows if you are pregnant or breast feeding, or if you have diabetes. Tell your doctor if you have angina (chest pain) or low blood pressure. Your doctor will need to know if you have a history of liver or gallbladder disease, ulcers, gout, or jaundice (skin or eyes turn yellow).
Follow your doctor's instructions carefully if you are switching to this medicine from another form of niacinamide. The dose may be different if you switch from the regular tablet to the extended-release tablet.
Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
This medicine may cause a warmth or redness in your face, neck, arms, or upper chest. This is called "flushing," and it usually improves after you have been taking niacinamide on a regular basis for a few weeks. To help prevent flushing, do not drink alcohol or hot drinks when you take this medicine, and do not take it on an empty stomach. You should also ask your doctor about taking aspirin or an anti-inflammatory medicine (such as ibuprofen) before you use this medicine.