You should not use this medicine if you have had an allergic reaction to nilotinib, or if you are pregnant. Do not use this medicine if you have low potassium or magnesium in your blood, or heart rhythm problem called long QT syndrome.
Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
It is best to take this medicine on an empty stomach. Take the medicine at least 1 hour before eating or 2 hours after eating.
Swallow the capsule whole with water. Do not open the capsules.
This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Your doctor might ask you to sign some forms to show that you understand this information.
If a dose is missed:
If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
Keep all medicine away from children and never share your medicine with anyone.
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are using certain antibiotics (such as clarithromycin, rifabutin, rifampin, rifapentin, telithromycin, Biaxin®, Ketek®, Mycobutin®, Rifadin®, Rimactane®, or Priftin®), medicine to treat fungal infections (such as itraconazole, ketoconazole, voriconazole, Nizoral®, Sporanox®, or Vfend®), or medicine to treat HIV or AIDS (such as atazanavir, indinavir, nelfinavir, ritonavir, saquinavir, Crixivan®, Fortovase®, Invirase®, Norvir®, Reyataz®, or Viracept®).
Tell your doctor if you are also using a blood thinner (such as warfarin or Coumadin®), medicine for seizures (such as carbamazepine, midazolam, phenobarbital, phenytoin, Dilantin®, Tegretol®, or Versed®), dexamethasone (Decadron®), nefazodone (Serzone®), or St. John's wort.
Do not eat grapefruit or drink grapefruit juice while you are using this medicine.
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
Make sure your doctor knows if you are breastfeeding, or if you have heart problems; liver problems; pancreatitis (inflammation of the pancreas); or high potassium or low calcium, phosphate, or sodium in your blood.
This medicine contains lactose. Tell your doctor if you have problems when taking lactose.
This medicine can cause changes in heart rhythms, such as a condition called QT prolongation. It may change the way your heart beats and cause fainting or serious side effects in some patients. Tell your doctor right away if you have any symptoms of heart rhythm problems, such as fast, pounding, or irregular heartbeats.
This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.
Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.