Treats the abnormal head position and neck pain that result from cervical dystonia (severe muscle spasms of the neck). Treats uncontrolled muscle spasms in the eyelids (blepharospasm) or around the eyes (strabismus). Treats excessive underarm sweating (hyperhidrosis). Also used to improve the appearance of deep facial lines or wrinkles between the eyebrows (glabellar lines). This is a botulinum toxin A product.
You should not receive this medicine if you have had an allergic reaction to onabotulinumtoxinA or any type of botulinum toxin product. You should not receive this medicine if you have an infection in the skin where the shot will be given.
Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
A nurse or other trained health professional will give you this medicine.
You may be given medicine to numb the area where the shot will be injected. If you receive the medicine around your eyes, you may be given eye drops or ointment to numb the area. After your injection, you may need to wear a protective contact lens or eye patch.
If you are treated for excessive sweating, shave your underarms but do not use deodorant for 24 hours before your injection. Avoid exercise, hot foods or liquids, or anything else that could make you sweat for 30 minutes before your injection.
This medicine works slowly. For neck disorders, you should have improvement within 2 to 6 weeks after your injection. Eyelid disorders should improve within 3 days to 2 weeks after your injection. Strabismus should improve within 1 or 2 days after the injection, and the improvement should last for 2 to 6 weeks. Once your condition has improved, the medicine will last about 3 months, then the effects of the medicine will slowly go away. You might need more injections when the effects of the medicine wear off.
Your doctor will only use onabotulinumtoxinA (Botox® or Botox® Cosmetic) to treat your condition. Other botulinum toxin products may not work the same way.
This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Your doctor might ask you to sign some forms to show that you understand this information.
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using quinidine (Cardioquin®), magnesium sulfate, medicine for an infection (such as amikacin, clindamycin, gentamicin, lincomycin, neomycin, netilmicin, polymyxin B, streptomycin, tobramycin, Amikin®, Garamycin®, or Netromycin®), or a muscle relaxant that would be used during surgery (such as atracurium, gallamine, pancuronium, succinylcholine, tubocurarine, vecuronium, Flaxedil®, Norcuron®, Pavulon®, Quelicin®, Tracrium®, or Tubarine®).
If you need to receive an injection of any botulinum toxin product within 4 months after receiving this medicine, tell the doctor when you last received a dose of onabotulinumtoxinA.
Make sure your doctor knows if you are pregnant or breastfeeding, or if you have breathing problems (such as asthma or emphysema), bladder problems, a droopy eyelid, heart disease, heart rhythm problems, or had a recent heart attack. Tell your doctor if you have nerve or muscle problems, amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), Lambert-Eaton syndrome (a nerve and muscle disorder), or myasthenia gravis (severe muscle weakness). Tell your doctor if you have trouble with speaking or swallowing, have a skin problem called dermatochalasis, or had face surgery in the past.
One part of this medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines made of human blood has been greatly reduced in recent years. This is the result of required testing of human donors for certain viruses, and required testing during the manufacture of these medicines. Although the risk is low, talk with your doctor if you have concerns.
After you receive this medicine and your vision or muscle spasms are better, you may be more active than you were before. You should slowly increase your activities to allow time for your body to get stronger. Also, before you start an exercise program, check with your doctor.
Serious muscle reactions have been reported within hours to weeks after receiving this medicine. If you start to have muscle weakness, loss of bladder control, or trouble with swallowing, talking, or breathing, call your doctor right away. In some patients, these problems could be life-threatening and may require treatment in a hospital or clinic.
This medicine may make your muscles weak and cause vision problems. Avoid driving, using machines, or doing anything else that could be dangerous if you feel weak or are not able to see well.
This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are using this medicine.
Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.