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Pentamidine (Injection)

Introduction:

Pentamidine (pen-TAM-i-deen)

Treats Pneumocystis carinii pneumonia (PCP) and other types of infections.

Brand Name(s):

Pentam

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to pentamidine.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given.
  • An IM shot is given in your muscle (upper arm, thigh, buttocks).
  • An IV is medicine that is put directly into your body through one of your veins.
  • This medicine should be given by a person trained to give IV or IM medicine, such as a nurse.
  • It is best to lie down while this medicine is given. To avoid dizziness, get up slowly.

If a dose is missed:

  • This medicine needs to be given on a regular schedule. If you miss a dose, call your doctor for instructions.

How to Store and Dispose of This Medicine:

  • Store your medicine at room temperature, away from heat and light.
  • Any pentamidine that has been prepared for the IV is good for 24 hours and should be kept at room temperature, away from heat and light.
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • Before using this medicine, make sure your doctor knows if you have low blood pressure, diabetes, low blood sugar, or liver or kidney disease.
  • You may need to use a home glucose (sugar) test to check your blood sugar levels while you are taking this medicine. Make sure you understand how to do this.
  • Your doctor may want to check your blood on a regular schedule while you are using pentamidine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Slow, fast, or irregular heartbeat
  • Feeling very hungry or thirsty
  • Nervousness, sweating, confusion
  • Unusual bleeding or bruising
  • Sore mouth or throat
  • Skin rash, itching, or hives
  • Trouble breathing

If you notice these less serious side effects, talk with your doctor:

  • Pain, swelling, itching, or burning where the IV is given
  • Nausea, vomiting, loss of appetite
  • Change in taste or a metallic taste in your mouth
  • Reviewed last on: 1/4/2010
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