You should not receive this medicine if you have had an allergic reaction to prilocaine or certain other types of local anesthetic (numbing medicine). You should not receive this medicine if you have methemoglobinemia, a blood disorder.
Make sure your doctor knows if you are pregnant or breast feeding, or if you have a history of glucose-6 phosphate deficiency (a blood disorder that causes anemia). Make sure your doctor knows if you have heart disease, heart rhythm problems, blood pressure problems, atherosclerosis (hardening of the arteries), or other circulation problems. Tell your doctor if you have liver disease, or any other health problems or drug allergies you may have.
Numbness may last for several hours after receiving this medicine. There is an increased risk of injury to your tongue, lips, and the inside of your cheeks until this medicine wears off. To avoid injury, do not chew solid foods until normal feeling has returned to the area. Do not test the feeling in your mouth by biting or poking at or in your mouth.
Make sure any doctor who treats you in the next week knows that you received this medicine. This medicine may affect the results of certain blood tests used to check your heart.