Romiplostim (Injection)

Introduction:

Romiplostim (roe-mi-PLOE-stim)

Treats low blood platelet counts and helps prevent bleeding in patients with a blood disorder called idiopathic thrombocytopenic purpura (ITP). This medicine is only used when surgery and other medicines have not worked well enough.

Brand Name(s):

Nplate

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• A doctor or other trained health professional will give you this medicine. This medicine is given as a shot under your skin.
• This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Your doctor might ask you to sign some forms to show that you understand this information.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breastfeeding, or if you have bleeding problems, bone marrow problems, a blood cancer, or a history of blood clots. Also tell your doctor if you have already had surgery to remove your spleen.
• Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
• Chest pain, shortness of breath, or coughing up blood.
• Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
• Pain in your lower leg (calf).
• Pinpoint red spots on the skin.
• Sudden or severe headache, problems with vision, speech, or walking.
• Unusual bleeding or bruising, or blood in the urine or stools.
• Weakness in your arm or leg, or on one side of your body.

If you notice these less serious side effects, talk with your doctor:

• Headache or dizziness.
• Muscle or joint pain, or pain in your shoulders, arms, or legs.
• Stomach pain or upset.
• Trouble sleeping.

If you notice other side effects that you think are caused by this medicine, tell your doctor: