You should not use this medicine if you have had an allergic reaction to ticlopidine, or if you have severe liver disease, a bleeding disorder or active bleeding (such as a bleeding ulcer or a head injury), or a condition called thrombocytopenic purpura (TTP).
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using antacids (Maalox®, Mylanta®), blood thinners (Coumadin®), cimetidine (Tagamet®), phenytoin (Dilantin®), propranolol (Inderal®), theophylline, or pain or arthritis medicine (such as aspirin, diclofenac, etodolac, ibuprofen, Advil®, Aleve®, Orudis®, Daypro®, Feldene®, Indocin®, Relafen®, Voltaren®).
Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, or have recently been injured or had surgery.
Your doctor will need to check your blood at regular visits while you are using this medicine. It is very important that you keep all appointments for blood tests.
This medicine can lower the number of certain types of blood cells in your body. Because of this, you may be more likely to get an infection or illness, and you may bleed more easily. To prevent these problems, avoid being near people who are sick or have infections. Wash your hands often. Avoid activities or situations in which you may get cut, bruised, or injured. Brush and floss your teeth gently. Use an electric razor instead of a razor blade when shaving.
Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine for 10 to 14 days before having surgery.