Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
Keep using any other asthma medicines your doctor may have prescribed for you. You should not use less or stop using your other medicines unless your doctor has told you to.
To control your asthma, you will need to use this medicine every day as ordered. It may take a few days or weeks before the medicine works. Keep using the medicine as your doctor ordered.
Take the extended-release tablet within one hour after your morning and evening meals.
Swallow the extended-release tablet whole. Do not crush, break, or chew it.
If a dose is missed:
If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
Keep all medicine away from children and never share your medicine with anyone.
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are using theophylline (Theo-Dur®), a blood thinner (warfarin, Coumadin®), terfenadine (Seldane®, Seldane-D®), or blood pressure medicines, such as propranolol (Inderal®), metoprolol (Lopressor®), atenolol (Tenormin®), or nadolol (Corgard®).
Make sure your doctor knows if you are pregnant or breastfeeding, or if you have a history of any liver disease (such as hepatitis). Tell your doctor if you drink alcohol.
This medicine helps prevent asthma attacks. For the medicine to work, you will need to use it every day, even when you are not having problems with your asthma. If your asthma does not get better or if it gets worse while you are using this medicine, tell your doctor.
Zileuton will not stop a severe asthma attack after it has started. Your doctor may give you a medicine to inhale that will work quickly for a severe attack. If you are already using an inhaler medicine and start to need that medicine more often or use the maximum number of puffs allowed in a day, tell your doctor.
Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
Call your doctor right away if you have pain in the right upper part of your stomach, yellowing of the skin or the whites of the eyes, itching, or if you feel unusually tired or like you have the flu. These may be signs of liver problems.
This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed and have problems with sleep. If you or your caregiver notice any of these side effects, tell your doctor right away.