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Radiation sickness - Overview

Alternative Names

Radiation poisoning; radiation injury

Definition of Radiation sickness:

Radiation sickness is illness and symptoms resulting from excessive exposure to ionizing radiation.

There are two basic types of radiation: ionizing and nonionizing.

  • Nonionizing radiation comes in the form of light, radio waves, microwaves and radar. This kind of radiation usually does not cause tissue damage.
  • Ionizing radiation is radiation that produces immediate chemical effects on human tissue . X-rays, gamma rays, and particle bombardment (neutron beam, electron beam, protons, mesons, and others) give off ionizing radiation. This type of radiation can be used for medical testing and treatment, industrial and manufacturing purposes, weapons and weapons development, and more.

Considerations:

Radiation sickness results when humans (or other animals) are exposed to very large doses of ionizing radiation.

Radiation exposure can occur as a single large exposure (acute), or a series of small exposures spread over time (chronic). Exposure may be accidental or intentional (as in radiation therapy).

Radiation sickness is generally associated with acute exposure and has a characteristic set of symptoms that appear in an orderly fashion. Chronic exposure is usually associated with delayed medical problems such as cancer and premature aging, which may happen over a long period of time.

The risk of cancer depends on the dose and begins to build up even with very low doses. There is no "minimum threshhold."

Exposure from x-rays or gamma rays is measured in units of roentgens. For example:

  • Total body exposure of 100 roentgens/rad (or 1 Gy) causes radiation sickness.
  • Total body exposure of 400 roentgens/rad (or 4 Gy) causes radiation sickness and death in half the individuals. Without medical treatment, nearly everyone who receives more than this amount of radiation will die within 30 days.
  • 100,000 roentgens/rad (1000 Gy) causes almost immediate unconsciousness and death within an hour

The severity of symptoms and illness (acute radiation sickness) depends on the type and amount of radiation, how long you were exposed, and which part of the body was exposed. Symptoms of radiation sickness may occur immediately after exposure, or over the next few days, weeks, or months. The bone marrow and gastrointestinal tract are especially sensitive to radiation injury. Children and babies still in the womb are more likely to be severely injured by radiation.

Because it is difficult to determine the amount of radiation exposure from nuclear accidents, the best signs of the severity of the exposure are: the length of time between the exposure and the onset of symptoms, the severity of symptoms, and severity of changes in white blood cells. If a person vomits less than an hour after being exposed, that usually means the radiation dose received is very high and death may be expected.

Children who receive radiation treatments or who are accidentally exposed to radiation will be treated based on their symptoms and their blood cell counts. Frequent blood studies are necessary and require a small puncture through the skin into a vein to obtain blood samples.

Causes:

The causes include:

  • Accidental exposure to high doses of radiation such as a nuclear power plant accidents
  • Exposure to excessive radiation for medical treatments
  • Reviewed last on: 1/12/2011
  • Jacob L. Heller, MD, MHA, Emergency Medicine, Virginia Mason Medical Center, Seattle, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Feldman R. Radiation injury. In: Schaider JJ, Hayden SR, Wolfe RE, Barkin RM, Rosen P, eds. Rosen and Barkin’s 5-Minute Emergency Medicine Consult. 3rd ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2007.

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