Symptoms:

There may be no symptoms. When symptoms occur, they can involve almost any body part or organ system in your body.

Almost all patients have lung or chest symptoms:

• Chest pain (most often behind your breast bone)
• Dry cough
• Shortness of breath

Symptoms of general discomfort or uneasiness often occur:

• Fatigue (one of the most common symptoms in children)
• Fever
• Joint achiness or pain (arthralgia)
• Overall feeling of discomfort, illness, or lack of well-being
• Weight loss (one of the most common symptoms in children)

Skin symptoms:

• Hair loss
• Raised, red, firm skin sores (erythema nodosum), almost always on the front part of the lower legs
• Rash
• Scars that become raised or inflamed

Nervous system symptoms may include:

• Headache
• Seizures
• Weakness on one side of the face

Eye symptoms include:

• Burning
• Discharge from the eye
• Dry eyes
• Itching
• Pain
• Vision loss

Other symptoms of this disease:

• Dry mouth
• Fainting spells if the heart is involved
• Nosebleed
• Swelling in the upper part of the abdomen

Signs and tests:

A physical exam may show the following:

• Abnormal breath sounds (such as rales)
• Enlarged liver
• Enlarged lymph glands
• Enlarged spleen
• Rash

Often the disease is found in patients with visible physical signs who have an abnormal chest x-ray.

Different imaging tests may help diagnose sarcoidosis:

• Chest x-ray to see if the lungs are involved or lymph nodes are enlarged
• CT scan of the chest
• Lung gallium scan

To diagnose this condition, a biopsy is needed. Biopsy of the lung using bronchoscopy is usually done. Biopsies of other body tissues may also be done.

This disease may affect the results of the following lab tests:

• Calcium levels (urine, ionized, serum)
• CBC
• Immunoelectrophoresis - serum
• Liver function tests
• Quantitative immunoglobulins (nephelometry)
• Serum phosphorus