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The mainstay of treatment for atypical pneumonia is antibiotic therapy. In mild cases, treatment with oral antibiotics at home may be appropriate. Severe cases (especially common with pneumonia caused by Legionella ) may require intravenous antibiotics and oxygen supplementation.
Antibiotics with activity against these organisms include -- erythromycin, azithromycin, clarithromycin, fluoroquinolones and their derivatives (such as levofloxacin), and tetracyclines (such as doxycycline).
Most patients with pneumonia due to Mycoplasma or Chlamydophila do well with appropriate antibiotic therapy, although there is a small chance of relapse if antibiotics are used for too short a period of time (less than two weeks).
In the case of pneumonia due to Legionella , severe illness occurs particularly among the elderly and those with chronic diseases and weakened immune systems. It is associated with a higher mortality rate.
Seek medical evaluation if you develop fevers, cough, and/or shortness of breath. While there are numerous causes for these symptoms, you will need to be evaluated for pneumonia.
Marx JA, Hockberger RS, Walls RM, eds. Rosen’s Emergency Medicine: Concepts and Clinical Practice. 5th ed. St. Louis, Mo: Mosby; 2002.
Cohen J, Powderly WG. Infectious Diseases . 2nd ed. New York, NY: Elsevier, 2004.
Mandell, GL, Bennett JE, Dolin R, eds. Principles of Infectious Diseases . 5th ed. New York, NY: Churchill Livingstone, 2000.
Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis . 2007 Mar 1;44 Suppl 2:S27-72.
American Thoracic Society. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med . 2005 Feb 15;171(4):388-416.
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