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Respiratory acidosis - Overview

Alternative Names

Ventilatory failure; Respiratory failure; Acidosis - respiratory

Definition of Respiratory acidosis:

Respiratory acidosis is a condition that occurs when the lungs cannot remove all of the carbon dioxide the body produces. This disrupts the body's acid-base balance causing body fluids, especially the blood, to become too acidic.

Causes, incidence, and risk factors:

Causes of respiratory acidosis include:

  • Diseases of the airways (such as asthma and chronic obstructive lung disease), which send air into and out of the lungs
  • Diseases of the chest (such as scoliosis), which make the lungs less efficient at filling and emptying
  • Diseases affecting the nerves and muscles that "signal" the lungs to inflate or deflate
  • Drugs that suppress breathing (including powerful pain medicines, such as narcotics, and "downers," such as benzodiazepines), especially when combined with alcohol
  • Severe obesity, which restricts how much the lungs can expand

Chronic respiratory acidosis occurs over a long period of time. This leads to a stable situation, because the kidneys increase body chemicals, such as bicarbonate, that help restore the body's acid-base balance.

Acute respiratory acidosis is a severe condition in which carbon dioxide builds up very quickly and before the kidneys can return the body to a state of balance.

  • Reviewed last on: 8/8/2009
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Seifter, JL. Acid base disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier. 2007: chap 119.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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