Histoplasmosis - chronic pulmonary - Symptom
Chronic cavitary histoplasmosis
- Cough that brings up blood, mucus, or pus
- Shortness of breath
- Unintentional weight loss
Signs and tests:
Tests that may be used to diagnose chronic pulmonary histoplasmosis include:
- Biopsy of infected tissue, such as open lung biopsy
- Bronchoscopy with transbronchial biopsy or bronchoalveolar lavage
- Chest CT scan
- Chest x-ray
- Histoplasma complement fixation titer
- Histoplasma urinary antigen test (positive only if the person also has disseminated histoplasmosis)
- Immunodiffusion test
- Sputum culture and stain
- Reviewed last on: 12/1/2009
- David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Kauffman CA. Histoplasmosis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 353.
What LJ, Freifeld AG, Kleiman MB, Baddley JW, McKinsey DS, Loyd JE, Kauffman CA. Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America. Clin Infect Dis, 2007;45(7):807-825.
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