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Blastomycosis - Treatment

Alternative Names

North American blastomycosis; Gilchrist's disease

Treatment:

Medicines may not be needed for a blastomycosis infection that stays in the lungs, unless it becomes severe. When the disease is severe, or when it spreads outside of the lungs, the following medicines (anti-fungals) may be prescribed:

  • Fluconazole
  • Itraconazole
  • Ketoconazole

Amphotericin B may be used for severe infections.

Follow-up regularly with your doctor to make sure the infection doesn't return.

Expectations (prognosis):

Patients with minor skin sores (lesions) and relatively mild lung infections usually recover completely. If the infection is not treated, it can become severe enough to cause death.

Complications:

  • Large sores with pus (abscesses)
  • Return of the infection (relapse or disease recurrence)
  • Side effects from drugs such as amphotericin B

Calling your health care provider:

Call your health care provider if you have symptoms of blastomycosis.

  • Reviewed last on: 9/17/2008
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Jatin M. Vyas, PhD, MD, Instructor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Chapman SW. Plastomyces dermatitidis. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 6th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2005: chap 263.

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