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Blastomycosis - Treatment

Alternative Names

North American blastomycosis; Gilchrist's disease

Treatment:

Medicines may not be needed for a blastomycosis infection that stays in the lungs, unless it becomes severe. When the disease is severe, or when it spreads outside of the lungs, the following medicines (anti-fungals) may be prescribed:

  • Fluconazole
  • Itraconazole
  • Ketoconazole

Amphotericin B may be used for severe infections.

Follow-up regularly with your doctor to make sure the infection doesn't return.

Expectations (prognosis):

Patients with minor skin sores (lesions) and relatively mild lung infections usually recover completely. If the infection is not treated, it can become severe enough to cause death.

Complications:

  • Large sores with pus (abscesses)
  • Return of the infection (relapse or disease recurrence)
  • Side effects from drugs such as amphotericin B

Calling your health care provider:

Call your health care provider if you have symptoms of blastomycosis.

  • Reviewed last on: 9/15/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Kauffman CA. Blastomycosis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 355.

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