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Pulmonary alveolar proteinosis - Overview

Alternative Names

Alveolar proteinosis

Definition of Pulmonary alveolar proteinosis:

Pulmonary alveolar proteinosis is a rare disease in which a type of protein builds up in the air sacs (alveoli) of the lungs, making breathing difficult.

Causes, incidence, and risk factors:

In some cases, the cause of pulmonary alveolar proteinosis is unknown. In others, it is associated with infection or an immune problem. It also can occur with cancers of the blood system, and after exposure to high levels of dust.

This rare disorder generally affects people 30 - 50 years old and is seen in men more often than in women. A form of the disorder is present at birth (congenital).

  • Reviewed last on: 5/21/2009
  • Allen J. Blaivas, D.O., Division of Pulmonary and Critical Care Medicine, UMDNJ-New Jersey Medical School, Newark, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Mason RJ, Broaddus VC, Murray JF, Nadel, JA. Murray and Nadel's Textbook of Respiratory Medicine. 4th ed. Philadelphia, Pa: WB Saunders; 2005.

Levine SM. Alveolar filling disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 91.

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