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Mesothelioma - malignant - Overview

Alternative Names

Malignant mesothelioma

Definition of Mesothelioma - malignant:

Malignant mesothelioma is an uncommon cancerous tumor of the lining of the lung and chest cavity (pleura) or lining of the abdomen (peritoneum) that is typically due to long-term asbestos exposure.

Causes, incidence, and risk factors:

Long-term exposure to asbestos -- a fire-resistant material -- is the biggest risk factor. Asbestos was once commonly found in insulation, ceiling and roofing vinyls, cement, and automotive brake materials. Although many asbestos workers smoked, experts do not believe smoking itself is a cause of this condition.

Malignant mesothelioma affects men more often than women. The average age at diagnosis is 60.

  • Reviewed last on: 6/2/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

National Comprehensive Cancer Network. Clinical practice guidelines in oncology. Malignant pleural mesothelioma. v.1.2010.

Lewis RL. Lung cancer and other pulmonary neoplasms. In Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 201.

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