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Renovascular hypertension - Overview

Alternative Names

Renal hypertension; Hypertension - renovascular; Renal artery occlusion; Stenosis - renal artery; Renal artery stenosis

Definition of Renovascular hypertension:

Renovascular hypertension is high blood pressure due to narrowing of the arteries that carry blood to the kidneys. This condition is also called renal artery stenosis.

See: High blood pressure

Causes, incidence, and risk factors:

When the arteries that carry blood to your kidneys become narrow, less blood flows to the kidneys. The kidneys mistakenly respond as if your blood pressure is low and give off hormones that tell the body to hold on to more salt and water. This causes your blood pressure to rise.

Renal artery stenosis is a narrowing or blockage of the artery that supplies blood to the kidneys.

The most common cause of renal artery stenosis is hardening of the arteries (atherosclerosis) from high cholesterol. This problem occurs when a sticky, fatty substance called plaque builds up on the inner lining of the arteries. The plaque may slowly narrow or even block the renal (kidney) artery.

Risk factors for atherosclerosis include high blood pressure, smoking, diabetes, high cholesterol, heavy alcohol use, cocaine abuse, and increasing age.

Fibromuscular dysplasia is another cause of renal artery stenosis. It is often seen in women under age 50 and tends to run in families.Fibromuscular dysplasia is caused by abnormal growth of cells in the walls of the arteries leading to the kidneys. This also leads to narrowing or blockage of these arteries.

  • Reviewed last on: 5/23/2011
  • David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc., and Michael A. Chen, MD, PhD, Assistant Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, Washington.

References

Victor RG. Systemic hypertension: Mechanisms and diagnosis. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 45.

Kaplan NM. Systemic hypertension: Therapy. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 46.

Dworkin LD, Murphy T. Is there any reason to stent atherosclerotic renal artery stenosis? Am J Kidney Dis. 2010 Aug;56(2):259-63.

U.S. Preventive Services Task Force. Screening for high blood pressure: U.S. Preventive Services Task Force reaffirmation recommendation statement. Ann Intern Med. 2007;147(11):783-786.

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