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Cholestasis - Treatment

Alternative Names

Intrahepatic cholestasis; Extrahepatic cholestasis

Treatment:

The underlying cause of cholestasis must be treated.

Expectations (prognosis):

How well a person does depends on the disease causing the condition. Stones in the common bile duct usually can be removed, curing the cholestasis.

Stents can be placed to open areas of the common bile duct that are narrowed or blocked by cancers.

Complications:

  • Diarrhea
  • Organ failure can occur if sepsis develops
  • Poor absorption of fat and fat-soluble vitamins
  • Severe itching
  • Weak bones (osteomalacia) and osteoporosis (due to very long-term cholestasis)

Calling your health care provider:

Call your health care provider if you have:

  • Persistent itching
  • Yellow skin or eyes
  • Other symptoms of cholestasis
  • Reviewed last on: 5/23/2010
  • David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc., and George F Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, California.

References

Zollner G, Trauner M. Mechanisms of cholestasis. Clinics in Liver Disease. 2008;12:1-26.

Afdhal NH. Diseases of the gallbladder and bile ducts. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 159.

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