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Helicobacter pylori - Overview

Alternative Names

Gastritis - Helicobacter pylori; H. pylori

Definition of Helicobacter pylori :

Helicobacter pylori (H. pylori) is the bacteria responsible for most ulcers and many cases of stomach inflammation (chronic gastritis).

The bacteria can weaken the protective coating of the stomach, allowing digestive juices to irritate the sensitive stomach lining.

Causes, incidence, and risk factors:

As many as half of the world's population is infected with H. pylori. Those living in developing countries or crowded, unsanitary conditions are most likely to contract the bacterium, which is passed from person to person. H. pylori only grows in the stomach, and is usually contracted during childhood.

Interestingly, many people have this organism in their stomach, but don't get an ulcer or gastritis. It seems that other factors must also be present for the damage to take place. The factors that increase your risk for an ulcer from H. pylori include:

  • Abnormal immune response in your stomach
  • Certain lifestyle habits, like coffee drinking, smoking, and alcohol consumption
  • Reviewed last on: 9/7/2008
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Chey WD, Wong BC. American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Am J Gastroenterol. Aug 2007;102(8):1808-25.

Ables AZ, Simon I, Melton ER. Update on Helicobacter pylori treatment. Am Fam Physician. 2007;75(3):351-358.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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