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Achalasia - Overview

Alternative Names

Esophageal achalasia

Definition of Achalasia:

Achalasia is a disorder of the tube that carries food from the mouth to the stomach (esophagus), which affects the ability of the esophagus to move food toward the stomach

Causes, incidence, and risk factors:

The main problem in achalasia is a failure of the a muscular ring where the esophagus and stomach come together (lower esophageal sphincter) to relax during swallowing.

Another part of the disorder is a lack of nerve stimulation to the muscles of the esophagus. Causes include:

  • Cancers
  • Damage to the nerves of the esophagus
  • Infection with a parasite
  • Inherited factors

As a result, the wave-like contractions of smooth muscles that normally force food through the esophagus and other parts of the digestive tract do not work as well. (These contractions are called peristalsis.)

Achalasia is a rare disorder. It may occur at any age, but is most common in middle-aged or older adults.

  • Reviewed last on: 2/20/2008
  • Christian Stone, MD, Division of Gastroenterology, Washington University in St. Louis, School of Medicine, St. Louis, MO. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Goldman L, Ausiello DA, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007.

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