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Hepatitis B - Treatment

Treatment:

Acute hepatitis needs no treatment other than careful monitoring of liver and other body functions with blood tests. You should get plenty of bed rest, drink plenty of fluids, and eat healthy foods.

In the rare case that you develop liver failure, you may need a liver transplant. A liver transplant is the only cure in some cases of liver failure.

Some patients with chronic hepatitis may be treated with antiviral medications or a medication called peginterferon. These medications can decrease or remove hepatitis B from the blood and reduce the risk of cirrhosis and liver cancer.

Liver transplantation is used to treat severe, chronic hepatitis B liver disease.

Patients with chronic hepatitis should avoid alcohol and should always check with their doctor or nurse before taking any over-the-counter medications or herbal supplements. This even includes medications such as acetaminophen, aspirin, or ibuprofen.

See: Cirrhosis for information about treating more severe liver damage caused by hepatitis B.

Support Groups:

See: Liver disease support group

Expectations (prognosis):

The acute illness usually goes away after 2 - 3 weeks. The liver usually returns to normal within 4 - 6 months in almost all patients who are infected.

Some people develop chronic hepatitis.

  • Almost all newborns and about 50% of children who become infected with hepatitis B develop chronic hepatitis. Less than 5% of adults who are infected with the hepatitis B virus develop the chronic condition.
  • Chronic hepatitis B infection increases the risk for liver damage, including cirrhosis and liver cancer.
  • People who have chronic hepatitis B can transmit the infection. They are considered carriers of the disease, even if they do not have any symptoms.

Hepatitis B is fatal in about 1% of cases.

Complications:

There is a much higher rate of hepatocellular carcinoma in people who have chronic hepatitis B than in the general population.

Other complications may include:

  • Chronic persistent hepatitis
  • Cirrhosis
  • Fulminant hepatitis, which can lead to liver failure and possibly death

Calling your health care provider:

Call your health care provider if:

  • You develop symptoms of hepatitis B
  • Hepatitis B symptoms do not go away in 2 or 3 weeks, or new symptoms develop
  • You belong to a high-risk group for hepatitis B and have not yet received the HBV vaccine.
  • Reviewed last on: 11/23/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Dienstag JL. Hepatitis B virus infection. N Engl J Med. 2008;359:1486-1500.

Perrillo R. Hepatitis B and D. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, Pa: Saunders Elsevier;2010:chap 78.

Sorrell MF, Belongia EA, Costa J, Gareen IF, Grem JL, Inadomi JM, et al. National Institutes of Health Consensus Development Conference Statement: Management of hepatitis B. Ann Intern Med. 2009;150:104-10.

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