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Sclerosing cholangitis - Overview

Alternative Names

Primary sclerosing cholangitis

Definition of Sclerosing cholangitis:

Sclerosing cholangitis is swelling (inflammation) of the bile ducts of the liver without a known cause.

Causes, incidence, and risk factors:

In this condition, the bile ducts inside and outside the liver become narrowed and scarred. The cause is unknown.

The disease is associated with inflammatory bowel disease (Crohn's disease and ulcerative colitis), and genetic factors may also be responsible. Sclerosing cholangitis occurs more often in men than women. This disorder is rare in children.

  • Reviewed last on: 2/20/2008
  • Christian Stone, MD, Division of Gastroenterology, Washington University in St. Louis, School of Medicine, St. Louis, MO. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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