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Primary sclerosing cholangitis; PSC
The first symptoms are usually fatigue, yellowing of the skin and eyes (jaundice), and itching. However, some people may have no symptoms.
Other symptoms may include:
Some people do not have symptoms, but blood work reveals they have abnormal liver function. The doctor will rule out diseases that cause similar problems. For example, you will be checked for stones in the gallbladder or biliary tract.
Tests that show cholangitis include:
Blood tests include:
Gordon FD. Primary sclerosing cholangitis. Surg Clin North Am. 2008;88:1385-1407.
Tung BY, Kowdley KV. Sclerosing cholangitis and recurrent pyogenic cholangitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger & Fordtran's Gastrointestinal and Liver Disease. 8th ed. Philadelphia, Pa: Saunders Elsevier;2006:chap 65.
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