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Gilbert's disease - Overview

Alternative Names

Icterus intermittens juvenilis; Low-grade chronic hyperbilirubinemia; Familial non-hemolytic-non-obstructive jaundice; Constitutional liver dysfunction; Unconjugated benign bilirubinemia

Definition of Gilbert's disease:

Gilbert's disease is a common disorder passed down through families.It affects the way bilirubin is processed by the liver, and causes jaundice.

Causes, incidence, and risk factors:

Gilbert's disease affects up to 10% of people in some Caucasian populations. The condition is usually noncancerous (benign).

  • Reviewed last on: 4/23/2009
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Berk PD, Korenblat KM. Approach to the patient with jaundice or abnormal liver test results. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 150.

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