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Ectopic ADH secretion - Treatment

Alternative Names

SIADH; Syndrome of inappropriate antidiuretic hormone secretion

Treatment:

Treatment is aimed at removing the cause of the problem (for example, surgery to remove a tumor producing ADH).

Limiting fluid intake is another common treatment. This helps prevent excess water from building up in the body.

Patients in the hospital with ectopic ADH that does not respond to other treatments may be given tolvaptan by mouth (orally) and conivaptan through a vein (intravenous). These treatments block the effects of ADH.

  • Reviewed last on: 11/23/2009
  • Ari S. Eckman, MD, Division of Endocrinology and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Lin M, Liu SJ, Lim IT. Disorders of water imbalance. Emerg Med Clin North Am. 2005;23(3):749-770.

Gagel RF. Endocrine manifestations of tumors: "ectopic" hormone production. In: Goldman L, Ausiello D, eds. Cecil Medicine. Philadelphia, PA: Saunders; 2007:chap 188.

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