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Acromegaly - Symptom

Alternative Names

Somatotroph adenoma; Growth hormone excess; Pituitary giant

Symptoms:

  • Body odor
  • Carpal tunnel syndrome
  • Decreased muscle strength (weakness)
  • Easy fatigue
  • Enlarged bones of the face
  • Enlarged feet
  • Enlarged hands
  • Enlarged glands in the skin (sebaceous glands)
  • Enlarged jaw (prognathism) and tongue
  • Excessive height (when excess growth hormone production begins in childhood)
  • Excessive sweating
  • Headache
  • Hoarseness
  • Joint pain
  • Limited joint movement
  • Sleep apnea
  • Swelling of the bony areas around a joint
  • Thickening of the skin, skin tags
  • Widely spaced teeth
  • Widened fingers or toes due to skin overgrowth with swelling, redness, and pain

Other symptoms that may occur with this disease:

  • Excess hair growth in females
  • Weight gain (unintentional)

Signs and tests:

This disease may also change the results of the following tests:

  • Reviewed last on: 11/25/2009
  • Ari S. Eckman, MD, Division of Endocrinology and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Melmed S, Kleinberg D. Anterior pituitary. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, PA: Saunders Elsevier; 2008:chap 8.

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