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Hyperaldosteronism - primary and secondary - Overview

Alternative Names

Conn syndrome

Definition of Hyperaldosteronism - primary and secondary:

Primary and secondary hyperaldosteronism are conditions in which the adrenal gland releases too much of the hormone aldosterone.

Causes, incidence, and risk factors:

People with primary hyperaldosteronism have a problem with the adrenal gland that causes it to release too much aldosterone.

In secondary hyperaldosteronism, the excess aldosterone is caused by something outside the adrenal gland that mimics the primary condition.

Primary hyperaldosteronism used to be considered a rare condition, but some experts believe that it may be the cause of high blood pressure in some patients. Most cases of primary hyperaldosteronism are caused by a noncancerous (benign) tumor of the adrenal gland. The condition is most common in people ages 30 - 50.

Secondary hyperaldosteronism is usually due to high blood pressure. It is also related to disorders such as:

  • Reviewed last on: 7/26/2011
  • Nancy J. Rennert, MD, Chief of Endocrinology & Diabetes, Norwalk Hospital, Associate Clinical Professor of Medicine, Yale University School of Medicine, New Haven, CT. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Young Jr WF. Endocrine hypertension. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Textbook of Endocrinology. 5th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 16.

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